Alternative strategies for stroke care: a prospective randomised controlled trial.

Background: Organised specialist care for stroke improves outcome, but the merits of different methods of organisation are in doubt. This study compares the efficacy of stroke unit with stroke team or domiciliary care. Methods: A single-blind, randomised, controlled trial was undertaken in 457 acute...

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Publicado en:Lancet Vol. 356; no. 9233; pp. 894 - 900
Autores principales: Kalra L, Evans A, Perez I, Knapp M, Donaldson N, Swift CG, Kalra, L, Evans, A, Perez, I, Knapp, M, Donaldson, N, Swift, C G
Formato: research tables/charts randomized controlled trial Journal Article
Publicado: Lancet 9/9/2000
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 9/9/2000
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      pub: Lancet
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          Kalra L
          Evans A
          Perez I
          Knapp M
          Donaldson N
          Swift CG
          Kalra, L
          Evans, A
          Perez, I
          Knapp, M
          Donaldson, N
          Swift, C G
        affil: Department of Medicine, Guy's, King's and St Thomas's School of Medicine, London, UK
      sug:
        subj:
          Stroke Rehabilitation
          Multidisciplinary Care Team
          Rehabilitation Centers
          Home Rehabilitation
          Inpatients
          Outpatients
          Single-Blind Studies
          Odds Ratio
          Confidence Intervals
          Kruskal-Wallis Test
          Barthel Index
          Logistic Regression
          Kaplan-Meier Estimator
          Mortality
          Institutionalization
          Clinical Assessment Tools
          Cox Proportional Hazards Model
          Disability Evaluation
          Length of Stay
          Health Resource Utilization
          Male
          Female
          Aged
          Aged, 80 and Over
          Outcomes (Health Care)
          Acute Care
          Funding Source
          Human
          Aged: 65+ years
          Aged, 80 & over
          Male
          Female
      ab: Background: Organised specialist care for stroke improves outcome, but the merits of different methods of organisation are in doubt. This study compares the efficacy of stroke unit with stroke team or domiciliary care. Methods: A single-blind, randomised, controlled trial was undertaken in 457 acute-stroke patients (average age 76 years, 48% women) randomly assigned to stroke unit, general wards with stroke team support, or domiciliary stroke care, within 72 h of stroke onset. Outcome was assessed at 3, 6, and 12 months. The primary outcome measure was death or institutionalisation at 12 months. Analyses were by intention to treat. Findings: 152 patients were allocated to the stroke unit, 152 to stroke team, and 153 to domiciliary stroke care. 51 (34%) patients in the domiciliary group were admitted to hospital after randomisation. Mortality or institutionalisation at 1 year were lower in patients on a stroke unit than for those receiving care from a stroke team (21/152 [14%] vs 45/149 [30%]; p<0.001) or domiciliary care (21/152 [14%] vs 34/144 [24%]; p=0.03), mainly as a result of reduction in mortality. The proportion of patients alive without severe disability at 1 year was also significantly higher on the stroke unit compared with stroke team (129/152 [85%] vs 99/149 [66%]; p<0.001) or domiciliary care (129/152 [85%] vs 102/144 [71%]; p=0.002). These differences were present at 3 and 6 months after stroke. Interpretation: Stroke units are more effective than a specialist stroke team or specialist domiciliary care in reducing mortality, institutionalisation, and dependence after stroke.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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