The I' potential of the human auditory brainstem response to paired click stimuli.
When stimulated with an appropriate stimulus, the hair cells of the organ of Corti depolarize, causing the release of a neurotransmitter substance, which excites afferent VIIIth nerve dendrites. It is reasonable to hypothesize that excitatory postsynaptic potentials (EPSPs) generated by the dendrite...
| Publicado en: | Scandinavian Audiology Vol. 30; no. 1; pp. 50 - 61 |
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| Autores principales: | , , , |
| Formato: | research tables/charts tracings Journal Article |
| Publicado: |
Taylor & Francis Ltd
Supplement 52
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107033057&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 107033057 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01050397 BD3 jtl: Scandinavian Audiology issn: 01050397 maglogo: N pubinfo: dt: Supplement 52 vid: 30 iid: 1 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 107033057 2001056891 10.1080/010503901750069572 NLM11330919 107033057 ppf: 50 ppct: 11 formats: fmt: @attributes: type: P tig: atl: The I' potential of the human auditory brainstem response to paired click stimuli. aug: au: Davis-Gunter MJ Löwenheim H Gopal KV Moore EJ affil: Auditory Neuroscience Laboratory, Department of Audiology and Speech Sciences, Michigan State University, East Lansing, MI sug: subj: Evoked Potentials, Auditory, Brainstem Action Potentials Funding Source Experimental Studies Paradigms Acoustic Impedance Tests Descriptive Statistics Kendall's tau Correlation Coefficient Cochlea Cochlear Nerve Human ab: When stimulated with an appropriate stimulus, the hair cells of the organ of Corti depolarize, causing the release of a neurotransmitter substance, which excites afferent VIIIth nerve dendrites. It is reasonable to hypothesize that excitatory postsynaptic potentials (EPSPs) generated by the dendrites of the auditory nerve in turn initiate a compound action potential (CAP). The EPSP is thought to be the generator potential for the CAP, and may be recorded in auditory brainstem responses (ABRs) as the I' potential. Determining the anatomical origin of I' may enhance the sensitivity of the ABR technique in hair cell/dendrite/auditory nerve evaluations. Whether I' is of sensory or of neural origin is equivocal, and therefore I' is not well understood. To investigate this dilemma, ABRs were recorded from human subjects using standard and paired-click stimuli, and using subtraction methods to generate a derived ABR. Two early peaks, designated as I [sic] and I', occurred before wave I in the derived ABR. It was hypothesized that peaks I [sic] and I' represent the summating potential and the generator potential, generated by the cochlea and VIIIth nerve dendrites, respectively. pubtype: Academic Journal doctype: research tables/charts tracings Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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