Enterobacter species in a pediatric hospital: horizontal transfer or selection in individual patients?

Enterobacter species were studied longitudinally in a children's hospital. In total, 287 Enterobacter isolates were obtained from 171 children in 15 different wards (from March 1995 through April 1997). Strains were typed by random amplified polymorphic DNA and pulsed-field gel electrophoresis, whic...

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Publicado en:Journal of Infectious Diseases Vol. 184; no. 2; pp. 211 - 215
Autores principales: de Man P, van der Veeke E, Leemreijze M, van Leeuwen W, Vos G, van den Aker J, Verbrugh H, van Belkum A
Formato: research tables/charts Journal Article
Publicado: Oxford University Press / USA 7/15/2001
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 7/15/2001
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        atl: Enterobacter species in a pediatric hospital: horizontal transfer or selection in individual patients?
      aug:
        au:
          de Man P
          van der Veeke E
          Leemreijze M
          van Leeuwen W
          Vos G
          van den Aker J
          Verbrugh H
          van Belkum A
        affil: Depts of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center, Rotterdam, The Netherlands
      sug:
        subj:
          Enterobacteriaceae Infections Transmission
          Cross Infection Transmission
          Disease Transmission, Horizontal
          Cross Infection Epidemiology
          Enterobacteriaceae Infections Epidemiology
          Hospitals, Pediatric
          Netherlands
          Human
      ab: Enterobacter species were studied longitudinally in a children's hospital. In total, 287 Enterobacter isolates were obtained from 171 children in 15 different wards (from March 1995 through April 1997). Strains were typed by random amplified polymorphic DNA and pulsed-field gel electrophoresis, which were concordant in outcome. In total, 97 DNA types and 199 colonization events were identified. A predominant clone was isolated 111 times from 62 children; another clone was isolated 19 times from 10 patients. These clones caused 36% of all colonizations. In 34% of the children, Enterobacter clones were found in 2-4 patients. The remaining colonizations were due to unique Enterobacter isolates. A large proportion of the Enterobacter strains was acquired through cross-transmission. This finding contrasts with the prevailing opinion that resistant Enterobacter strains are selected primarily from the patient's own gut flora. © 2001 Infectious Diseases Society of America
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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