Improving the quality of reports of meta-analyses of randomised controlled trials: the QUOROM statement. Quality of Reporting of Meta-analyses.

Background: The Quality of Reporting of Meta-analyses (QUOROM) conference was convened to address standards for improving the quality of reporting of meta-analyses of clinical randomised controlled trials (RCTs).Methods: The QUOROM group consisted of 30 clinical epidemiologists, clinicians, statisti...

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Publicado en:Lancet Vol. 354; no. 9193; pp. 1896 - 1901
Autores principales: Moher D, Cook DJ, Eastwood S, Olkin I, Rennie D, Stroup DF, Moher, D, Cook, D J, Eastwood, S, Olkin, I, Rennie, D, Stroup, D F
Formato: algorithm research tables/charts Journal Article
Publicado: Lancet 11/27/1999
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Improving the quality of reports of meta-analyses of randomised controlled trials: the QUOROM statement. Quality of Reporting of Meta-analyses.
      aug:
        au:
          Moher D
          Cook DJ
          Eastwood S
          Olkin I
          Rennie D
          Stroup DF
          Moher, D
          Cook, D J
          Eastwood, S
          Olkin, I
          Rennie, D
          Stroup, D F
        affil: University of Ottawa, Thomas C Chalmers Centre for Systematic Reviews, Ontario, Canada
      sug:
        subj:
          Meta Analysis Standards
          Research Methodology
          Bias (Research)
          Checklists
          Delphi Technique
          Funding Source
          Human
          Literature Review
          Randomized Controlled Trials
          Systematic Review
          Validity
      ab: Background: The Quality of Reporting of Meta-analyses (QUOROM) conference was convened to address standards for improving the quality of reporting of meta-analyses of clinical randomised controlled trials (RCTs).Methods: The QUOROM group consisted of 30 clinical epidemiologists, clinicians, statisticians, editors, and researchers. In conference, the group was asked to identify items they thought should be included in a checklist of standards. Whenever possible, checklist items were guided by research evidence suggesting that failure to adhere to the item proposed could lead to biased results. A modified Delphi technique was used in assessing candidate items.Findings: The conference resulted in the QUOROM statement, a checklist, and a flow diagram. The checklist describes our preferred way to present the abstract, introduction, methods, results, and discussion sections of a report of a meta-analysis. It is organised into 21 headings and subheadings regarding searches, selection, validity assessment, data abstraction, study characteristics, and quantitative data synthesis, and in the results with "trial flow", study characteristics, and quantitative data synthesis; research documentation was identified for eight of the 18 items. The flow diagram provides information about both the numbers of RCTs identified, included, and excluded and the reasons for exclusion of trials.Interpretation: We hope this report will generate further thought about ways to improve the quality of reports of meta-analyses of RCTs and that interested readers, reviewers, researchers, and editors will use the QUOROM statement and generate ideas for its improvement.
      pubtype: Academic Journal
      doctype:
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        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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