Review: controlling house dust mites is ineffective for asthmatic patients who are sensitive to mites [commentary on Gotzsche PC, Hammarquist C, Burr M. House dust mite control measures in the management of asthma: meta-analysis. BR MED J 1998 Oct 24;317(7166):1105-10 and Hammarquist C, Burr ML, Gotzsche PC. House dust mite control measures for asthma (Cochrane Review, latest version 30 Apr 1998) In: Cochrane Library. Oxford: Update Software].
Question: Is a reduction in exposure to dust mite antigen in the home effective for patients with asthma who are sensitive to mites? Data sources: Studies were identified by searching the the Cochrane Airways Group databases, which contain citations from CINAHL, Medline, and Embase/Excerpta Medica....
| Publicado en: | Evidence Based Nursing pp. 79 - 80 |
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| Autor principal: | |
| Formato: | abstract commentary Journal Article |
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BMJ Publishing Group
Jul1999
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107098084&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 107098084 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13676539 C0J jtl: Evidence Based Nursing issn: 13676539 maglogo: N pubinfo: dt: Jul1999 pid: 8280 pub: BMJ Publishing Group artinfo: ui: 107098084 107098084 2000016551 107098084 ppf: 79 ppct: 1 formats: tig: atl: Review: controlling house dust mites is ineffective for asthmatic patients who are sensitive to mites [commentary on Gotzsche PC, Hammarquist C, Burr M. House dust mite control measures in the management of asthma: meta-analysis. BR MED J 1998 Oct 24;317(7166):1105-10 and Hammarquist C, Burr ML, Gotzsche PC. House dust mite control measures for asthma (Cochrane Review, latest version 30 Apr 1998) In: Cochrane Library. Oxford: Update Software]. aug: au: Fihe DM affil: Pulmonary Nurse Clinician, Children's Hospital Medical Centre of Akron, Akron, Ohio sug: subj: Home Environment Environment, Controlled Asthma Prevention and Control Mites Environmental Exposure Prevention and Control Clinical Trials Meta Analysis Data Analysis, Statistical Descriptive Statistics Peak Expiratory Flow Rate Forced Expiratory Volume Allergens Confidence Intervals Odds Ratio Treatment Outcomes Research Methodology ab: Question: Is a reduction in exposure to dust mite antigen in the home effective for patients with asthma who are sensitive to mites? Data sources: Studies were identified by searching the the Cochrane Airways Group databases, which contain citations from CINAHL, Medline, and Embase/Excerpta Medica. Respiration and Clinical and Experimental Allergy were handsearched (1980-96). Bibliographies of relevant articles were scanned, and primary authors were contacted for additional data. Study selection: Studies in any language were selected if they were randomised controlled trials that compared chemical or physical measures for controlling mites in the home with no treatment in patients with bronchial asthma. A diagnosis of asthma by a physician and confirmation of sensitisation to mites were required. Data extraction: 2 authors extracted data on subjective wellbeing, improvement in asthma symptoms, medication to control asthma, number of sick days, number of unscheduled visits to a physician or hospital, FEV1 (forced expiratory volume in 1 sec), peak expiratory flow rate, provocative concentration that causes a 20% decrease in FEV1 (PC[20]), and results of skin prick testing. Main results: 23 studies involving 686 adults and children met the inclusion criteria (1 study that had 3 groups was treated as 2 separate trials). Follow up ranged from 2-52 weeks (mean 18.6 wks). 13 studies used physical methods to control mites, and 3 reported a reduction in mite exposure (5 studies did not assess mite exposure). 6 studies used chemical methods to control mites, and none reported a reduction in mite exposure. 4 studies used a combination of methods, and 3 reported a reduction in mite exposure. Groups did not differ for number of patients who improved after intervention (5 studies), asthma symptom improvement (7 studies), peak expiratory flow rate in the morning (10 studies) or evening (6 studies), PC[20] (8 studies), or medication use (6 studies). Heterogeneity existed among trials for asthma symptom improvement (p < 0.001). Conclusion: A reduction in exposure to dust mite antigen in the home does not lead to an improvement in patients with asthma who are sensitive to mites. [Original article accession number: 1998074109 (clinical trial, research, tables/charts) and 2000006662 (research, systematic review, tables/charts) pubtype: Academic Journal doctype: abstract commentary Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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