Accurate diagnosis of Helicobacter pylori infection by stool antigen test and 6 other currently available tests in children.
Invasive and noninvasive tests have been developed for the diagnosis of Helicobacter pylori infection. Because H pylori infection is acquired in childhood and adolescence, accurate diagnosis of the infection in the pediatric population is important. We conducted a study to compare invasive tests: cu...
| Publicado en: | Journal of Pediatrics Vol. 136; no. 6; pp. 823 - 828 |
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| Autores principales: | , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Elsevier B.V.
2000 Jun
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107132295&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 107132295 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00223476 04M jtl: Journal of Pediatrics issn: 00223476 maglogo: N pubinfo: dt: 2000 Jun vid: 136 iid: 6 pid: 467 pub: Elsevier B.V. place: New York, New York artinfo: ui: 107132295 107132295 2000056342 NLM10839883 107132295 ppf: 823 ppct: 5 formats: tig: atl: Accurate diagnosis of Helicobacter pylori infection by stool antigen test and 6 other currently available tests in children. aug: au: Ni Y Lin J Huang S Yang J Chang M affil: Dept of Pediatrics, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan sug: subj: Helicobacter Infections Diagnosis Helicobacter Infections Diagnosis Convenience Sample Sensitivity and Specificity Descriptive Statistics Prospective Studies Child Adolescence Male Female Funding Source Human Child: 6-12 years Adolescent: 13-18 years Male Female ab: Invasive and noninvasive tests have been developed for the diagnosis of Helicobacter pylori infection. Because H pylori infection is acquired in childhood and adolescence, accurate diagnosis of the infection in the pediatric population is important. We conducted a study to compare invasive tests: culture, biopsy urease test, histology, and polymerase chain reaction on gastric biopsy specimens, with noninvasive tests: serology, (13)C-urea breath test, and a new diagnostic modality, stool antigen test to diagnose H pylori infection. A total of 53 children with symptoms were enrolled in this study, and all had completed the 7 diagnostic tests for H pylori. All the diagnostic tests except serology were excellent methods of diagnosing H pylori infection in children; the diagnostic accuracy was as follows: stool antigen test 96.2%, biopsy urease test 96.2%, histology 98.1%, polymerase chain reaction 94.3%, culture 98.1%, (13)C-urea breath test 100%, and serology 84.9%. The stool antigen test, being highly sensitive and specific, will be potentially very helpful in diagnosing H pylori infection in children. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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