A novel treatment for fibromyalgia improves clinical outcomes in a community-based study.
Objectives: Immunoreactant load was assessed by using lymphocyte response assay [LRA] with cell response/blastogenic mixed cell culture to determine if substitution of reactive items would be associated with remission of symptoms in subjects with fibromyalgia syndrome [FMS]. Methods: Fibromyalgia su...
| Publicado en: | Journal of Musculoskeletal Pain Vol. 6; no. 2; pp. 133 - 150 |
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| Autores principales: | , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
1998
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107181784&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 107181784 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10582452 88S jtl: Journal of Musculoskeletal Pain issn: 10582452 maglogo: N pubinfo: dt: 1998 vid: 6 iid: 2 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 107181784 107181784 1999027272 107181784 ppf: 133 ppct: 17 formats: tig: atl: A novel treatment for fibromyalgia improves clinical outcomes in a community-based study. aug: au: Deuster PA Jaffe RM affil: Health Studies Collegium, 1890 Preston White Drive, Reston, VA 22091 sug: subj: Fibromyalgia Immunology Fibromyalgia Therapy Hypersensitivity Prevention and Control Life Style Fibromyalgia Symptoms Funding Source Prospective Studies Quasi-Experimental Studies Treatment Outcomes Immunoassay Tissue Culture Techniques Antigens Diagnostic Use Antigen-Antibody Reactions Evaluation Questionnaires Self Report Pain Measurement Support Groups Fibromyalgia Diet Therapy Dietary Supplementation Environmental Exposure Prevention and Control Patient Compliance Descriptive Statistics Repeated Measures Analysis of Variance Data Analysis Software P-Value Sex Factors Age Factors Adult Middle Age Female Male Human Adult: 19-44 years Middle Aged: 45-64 years Female Male ab: Objectives: Immunoreactant load was assessed by using lymphocyte response assay [LRA] with cell response/blastogenic mixed cell culture to determine if substitution of reactive items would be associated with remission of symptoms in subjects with fibromyalgia syndrome [FMS]. Methods: Fibromyalgia subjects [N 51] were assigned to a control [C: N = I I] or treatment [T: N 40] group; C maintained usual life-styles and T, after LRA testing, underwent a program of substitution and nutritional repletion with metabolic intermediates. All subjects participated in biweekly support groups and completed questionnaires [0 months, three months, and six months] to document changes. Results: After six months T experienced 50% less pain, 70% less depression, 50% more energy, and 30% less stiffness, whereas C reported an increase in pain and depression, and comparable levels of stiffness and energy as compared to pre-program levels. Conclusions: These data suggest that reducing the inununoreactant load in FMS, while stimulating repair, may help re-establish homeostasis and neuroimmune hormonal control. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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