How a child builds its brain: some lessons from animal studies of neural plasticity.

Although the potential vulnerability of children's brain development is generally recognized, relatively little is known about the timing, resiliency, or mechanisms involved. While animal research should be applied only cautiously to human policy, some findings do have important clinical implication...

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Publicado en:Preventive Medicine Vol. 27; no. 2; pp. 168 - 172
Autor principal: Black JE
Formato: Journal Article
Publicado: Academic Press Inc. 1998 Mar-Apr
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 1998 Mar-Apr
      vid: 27
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      pub: Academic Press Inc.
      place: Burlington, Massachusetts
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        107185422
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        1999038106
        10.1006/pmed.1998.0271
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        atl: How a child builds its brain: some lessons from animal studies of neural plasticity.
      aug:
        au: Black JE
        affil: Beckman Institute, University of Illinois at Urbana-Champaign, 405 N. Mathews, Urbana, IL 61801. E-mail: jblacks@s.psych.uiuc.edu
      sug:
        subj:
          Brain
          Neuronal Plasticity
          Child Development
          Infant Development
          Animal Studies
          Infant, Newborn
          Infant
          Child, Preschool
          Child
          Infant, Newborn: birth-1 month
          Infant: 1-23 months
          Child, Preschool: 2-5 years
          Child: 6-12 years
      ab: Although the potential vulnerability of children's brain development is generally recognized, relatively little is known about the timing, resiliency, or mechanisms involved. While animal research should be applied only cautiously to human policy, some findings do have important clinical implications. This paper briefly reviews animal studies demonstrating the effects of experience on brain structure. Contemporary theories emphasize the self-organizing potential of brain structure, particularly regions that seem to have evolved for the purpose of storing information. We emphasize three major findings: (1) many regions of the brain are responsive to experience, but they differ in the types of information stored and in their developmental timing. (2) One type of plasticity is typically embedded in a developmental program, and it requires appropriate timing and quality of the information stored for the animal's development to be normal. (3) Another category of plasticity stores information that is idiosyncratic and unpredictable, but is often useful for species such as humans that learn throughout their life span. We therefore expect that some aspects of human brain development use the first type of plasticity and that abnormal experience or deprivation may cause lasting harm to brain and behavior. However, because the other type of plasticity lasts a lifetime, efforts such as psychotherapy or social interventions may help heal a wounded brain.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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