Pyoderma gangrenosum: tools to cope with this dermatologic emergency: roughly half of affected patients have an underlying associated condition.
A noninfectious, noninflammatory neutrophilic dermatosis, pyoderma gangrenosum usually manifests as a single ulcer or multiple ulcers of the leg. The primary lesion, either a pustule or vesicle, rapidly develops into a painful, irregularly shaped, purulent ulcer. A biopsy of a specimen obtained from...
| Publicado en: | Journal of Critical Illness Vol. 13; no. 4; pp. 260 - 265 |
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| Autores principales: | , |
| Formato: | pictorial tables/charts Journal Article |
| Publicado: |
Cliggott Publishing Company
1998 Apr
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107278190&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 107278190 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10400257 0OQ jtl: Journal of Critical Illness issn: 10400257 maglogo: N pubinfo: dt: 1998 Apr vid: 13 iid: 4 pid: 119 pub: Cliggott Publishing Company place: Greenwich, Connecticut artinfo: ui: 107278190 107278190 1998047666 107278190 ppf: 260 ppct: 5 formats: tig: atl: Pyoderma gangrenosum: tools to cope with this dermatologic emergency: roughly half of affected patients have an underlying associated condition. aug: au: Rothe MJ Grant-Kels JM affil: Department of Dermatology, University of Connecticut Health Center, Farmington sug: subj: Pyoderma Gangrenosum Pyoderma Gangrenosum Symptoms Pyoderma Gangrenosum Diagnosis Pyoderma Gangrenosum Therapy ab: A noninfectious, noninflammatory neutrophilic dermatosis, pyoderma gangrenosum usually manifests as a single ulcer or multiple ulcers of the leg. The primary lesion, either a pustule or vesicle, rapidly develops into a painful, irregularly shaped, purulent ulcer. A biopsy of a specimen obtained from the edge of the ulcer is key to ruling out such mimics as cutaneous carcinoma, lymphoma, vasculitis, and infection. Relatively small, stable ulcers may respond to local wound care and intermittent intralesional corticosteroid injections. Treat larger ulcers with prednisone alone or in combination with an agent to inhibit inflammation and neutrophil function. Cyclosporine may be an effective immunosuppressive alternative. For rapidly enlarging, disfiguring ulcers, treat with intravenous or pulse methylprednisolone, followed by gradually tapered prednisone, and a corticosteroid-sparing agent. pubtype: Academic Journal doctype: pictorial tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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