Treatment of leg ulcers with cultured epithelial autografts: treatment protocol and five year experience.
Leg ulcers are a significant medical problem in the United States. The number of affected patients at any given time is staggering. Treatment modalities have widely varied and are often unsuccessful. We evaluated the effectiveness of cultured epithelial autografts in the treatment of leg ulcers due...
| Publicado en: | Wounds: A Compendium of Clinical Research & Practice Vol. 7; no. 5; pp. 170 - 181 |
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| Autores principales: | , |
| Formato: | pictorial tables/charts Journal Article |
| Publicado: |
HMP Global
1995 Sep-Oct Supplement
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107367329&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 107367329 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10447946 YZM jtl: Wounds: A Compendium of Clinical Research & Practice issn: 10447946 maglogo: N pubinfo: dt: 1995 Sep-Oct Supplement vid: 7 iid: 5 pid: 20465 pub: HMP Global place: Malvern, Pennsylvania artinfo: ui: 107367329 107367329 1996016883 107367329 ppf: 170 ppct: 11 formats: tig: atl: Treatment of leg ulcers with cultured epithelial autografts: treatment protocol and five year experience. aug: au: Limova M Mauro T affil: Department of Dermatology, Medical Center at UCSF, 400 Parnassus Avenue, A316 San Francisco, CA 94143-0316 sug: subj: Leg Ulcer Therapy Autografts Epithelium Wound Healing Leg Ulcer Etiology Adult Middle Age Aged Male Female Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Leg ulcers are a significant medical problem in the United States. The number of affected patients at any given time is staggering. Treatment modalities have widely varied and are often unsuccessful. We evaluated the effectiveness of cultured epithelial autografts in the treatment of leg ulcers due to various etiologies that had failed other standard therapy. Eighty-six ulcers in 36 patients were treated with cultured epithelial autografts after full evaluation of their ulcers. The ulcers were grouped by etiology and healing was assessed by time to healing, number of ulcers healed and mean number of graft applications. The results achieved in the past five years have shown that cultured epithelial autografts are highly effective in treating chronic leg ulcers. Eighty percent of venous insufficiency ulcers healed in 5.7 weeks. Similar results were seen with ulcers of other etiologies including arterial insufficiency, pyoderma gangrenosum, scleroderma, and vasculitis. Positive results were seen in cases where other treatment methods had failed and seems independent of systemic corticosteroids. pubtype: Periodical doctype: pictorial tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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