Statistical conclusion validity: multiple inferences in rehabilitation research.

The problem of multiple statistical inferences and Type I error rates in rehabilitation research is examined. The Bonferroni method is the most commonly advocated procedure to control Type I error in clinical research. The traditional Bonferroni method is often overly conservative and results in a l...

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Bibliographic Details
Published in:American Journal of Physical Medicine & Rehabilitation Vol. 70; no. 6; pp. 317 - 323
Main Author: Ottenbacher KJ
Format: Journal Article
Published: Lippincott Williams & Wilkins 1991 Dec
Online Access:View this record in EBSCOhost
Description
Summary:The problem of multiple statistical inferences and Type I error rates in rehabilitation research is examined. The Bonferroni method is the most commonly advocated procedure to control Type I error in clinical research. The traditional Bonferroni method is often overly conservative and results in a loss of statistical power when more than a small number of comparisons are evaluated. Adjustments to the Bonferroni method designed to control or reduce the incidence of Type I errors and improve the statistical conclusion validity of rehabilitation research are presented. The adjusted or sharpened Bonferroni methods allow the researcher to control the incidence of Type I errors while maintaining statistical power. Adjustments to the Bonferroni method are simple to compute and applicable to a wide variety of statistical tests. The use of appropriate multiple comparison procedures will reduce the number of Type I errors and improve the statistical conclusion validity of rehabilitation research studies.