An independent analysis of the National Cancer Institute study on non-nutritive sweeteners and bladder cancer.

Abstract: We evaluated the possible relation between use of non-nutritive sweeteners and bladder cancer using data obtained from the National Cancer Institute Bladder Cancer Study under the Freedom of Information Act. In the general study group, there was no evidence for an association between non-n...

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Publicado en:American Journal of Public Health Vol. 72; no. 4; pp. 376 - 382
Autores principales: Walker AM, Dreyer NA, Friedlander E
Formato: Journal Article
Publicado: American Public Health Association Apr1982
Materias:
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr1982
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      pub: American Public Health Association
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        atl: An independent analysis of the National Cancer Institute study on non-nutritive sweeteners and bladder cancer.
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          Walker AM
          Dreyer NA
          Friedlander E
      su:
        Nonnutritive sweeteners
        National Cancer Institute (U.S.)
        Bladder diseases
        Urinary organ diseases
        Cancer
        Freedom of information
      sug:
        subj:
          Nonnutritive sweeteners
          National Cancer Institute (U.S.)
          Bladder diseases
          Urinary organ diseases
          Cancer
          Freedom of information
      ab: Abstract: We evaluated the possible relation between use of non-nutritive sweeteners and bladder cancer using data obtained from the National Cancer Institute Bladder Cancer Study under the Freedom of Information Act. In the general study group, there was no evidence for an association between non-nutritive sweeteners and bladder cancer. Control for a variety of factors through multivariate techniques diminished the plausibility of earlier interpretations of these data, which had raised the possibility that certain subgroups of users of non-nutritive sweeteners might be at an increased risk for bladder cancer. We found that the putative effects of non-nutritive sweeteners were not consistent among subgroups with similar baseline risk, did not display consistent dose-response trends, and were subject to considerable sampling error. We concluded that the data provided little evidence that non- nutritive sweeteners increase risk for bladder cancer among subgroups of users, and that definitive evidence on this question is beyond the reach of conventional research.
      pubtype: Academic Journal
      doctype: Journal Article
      src: R
    language: English
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