Differential transcript profiles of MHC class Ib(Qa-1, Qa-2, and Qa-10) and Aire genes during the ontogeny of thymus and other tissues.

Qa-2 and Qa-1 are murine nonclassical MHC class I molecules involved in the modulation of immune responses by interacting with T CD8(+) and NK cell inhibitory receptors. During thymic education, the Aire gene imposes the expression of thousands of tissue-related antigens in the thymic medulla, permi...

Descripción completa

Detalles Bibliográficos
Publicado en:Journal of Immunology Research Vol. 2014; pp. 159247 - 159248
Autores principales: Melo-Lima, Breno Luiz, Evangelista, Adriane Feijó, de Magalhaes, Danielle Aparecida Rosa, Passos, Geraldo Aleixo, Moreau, Philippe, Donadi, Eduardo Antonio, de Magalhães, Danielle Aparecida Rosa
Formato: research Journal Article
Publicado: Wiley-Blackwell 2014
Acceso en línea:Ver este registro en EBSCOhost