Dysregulation of autoantigen genes in ANCA-associated vasculitis involves alternative transcripts and new protein synthesis.

Proteinase 3 (PR3) and myeloperoxidase (MPO) are two major autoantigens in patients with vasculitis with ANCA. The genes encoding these autoantigens are abnormally expressed in peripheral granulocytes of patients with active ANCA-associated vasculitis. This study provides evidence that this transcri...

Full description

Bibliographic Details

Published in:	Journal of the American Society of Nephrology (JASN) Vol. 26; no. 2; pp. 390 - 400
Main Authors:	McInnis, Elizabeth A, Badhwar, Anshul K, Muthigi, Akhil, Lardinois, Olivier M, Allred, S Colby, Yang, Jiajin, Free, Meghan E, Jennette, J Charles, Preston, Gloria A, Falk, Ronald J, Ciavatta, Dominic J
Format:	research Journal Article
Published:	Lippincott Williams & Wilkins 2015 Feb
Online Access:	View this record in EBSCOhost