Alternative splicing generates a diacylglycerol kinase α transcript that acts as a dominant-negative modulator of superoxide production in localized aggressive periodontitis.

Background: Diacylglycerol (DAG), levels of which are tightly regulated by diacylglycerol kinases (DGKs), is a lipid mediator linked to key biologic functions. Members of the DGK family undergo alternative splicing, generating the protein diversity necessary to control different intracellular DAG po...

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Bibliographic Details

Published in:	Journal of Periodontology Vol. 85; no. 7; pp. 934 - 944
Main Authors:	Batista Jr, Eraldo L, Kantarci, Alpdogan I, Hasturk, Hatice, Van Dyke, Thomas E, Batista, Eraldo L Jr
Format:	research Journal Article
Published:	Wiley-Blackwell Jul2014
Online Access:	View this record in EBSCOhost