Hidden word learning capacity through orthography in aphasia.
The ability to learn to use new words is thought to depend on the integrity of the left dorsal temporo-frontal speech processing pathway. We tested this assumption in a chronic aphasic individual (AA) with an extensive left temporal lesion using a new-word learning paradigm. She exhibited severe pho...
| Publicado en: | Cortex: A Journal Devoted to the Study of the Nervous System & Behavior Vol. 50; pp. 174 - 192 |
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| Autores principales: | , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Masson SPA
2014 Jan
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107877128&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 107877128 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00109452 GMP jtl: Cortex: A Journal Devoted to the Study of the Nervous System & Behavior issn: 00109452 maglogo: N pubinfo: dt: 2014 Jan vid: 50 pid: 12473 pub: Masson SPA artinfo: ui: 107877128 107877128 NLM24262200 2012439637 10.1016/j.cortex.2013.10.003 NLM24262200 107877128 ppf: 174 ppct: 18 formats: tig: atl: Hidden word learning capacity through orthography in aphasia. aug: au: Tuomiranta, Leena M Càmara, Estela Froudist Walsh, Seán Ripollés, Pablo Saunavaara, Jani P Parkkola, Riitta Martin, Nadine Rodríguez-Fornells, Antoni Laine, Matti affil: Department of Psychology and Logopedics, Abo Akademi University, Turku, Finland. sug: subj: Aphasia Psychosocial Factors Aphasia Rehabilitation Learning Algorithms Aphasia Etiology Cluster Analysis Magnetic Resonance Imaging Female Dominance, Cerebral Physiology Human Image Processing, Computer Assisted Male Memory Middle Age Neural Pathways Anatomy and Histology Neural Pathways Physiology Neuropsychological Tests Postoperative Complications Psychosocial Factors Psychomotor Performance Reading Subarachnoid Hemorrhage Complications Vocabulary Middle Aged: 45-64 years Female Male ab: The ability to learn to use new words is thought to depend on the integrity of the left dorsal temporo-frontal speech processing pathway. We tested this assumption in a chronic aphasic individual (AA) with an extensive left temporal lesion using a new-word learning paradigm. She exhibited severe phonological problems and Magnetic Resonance Imaging (MRI) suggested a complete disconnection of this left-sided white-matter pathway comprising the arcuate fasciculus (AF). Diffusion imaging tractography confirmed the disconnection of the direct segment and the posterior indirect segment of her left AF, essential components of the left dorsal speech processing pathway. Despite her left-hemispheric damage and moderate aphasia, AA learned to name and maintain the novel words in her active vocabulary on par with healthy controls up to 6 months after learning. This exceeds previous demonstrations of word learning ability in aphasia. Interestingly, AA's preserved word learning ability was modality-specific as it was observed exclusively for written words. Functional magnetic resonance imaging (fMRI) revealed that in contrast to normals, AA showed a significantly right-lateralized activation pattern in the temporal and parietal regions when engaged in reading. Moreover, learning of visually presented novel word-picture pairs also activated the right temporal lobe in AA. Both AA and the controls showed increased activation during learning of novel versus familiar word-picture pairs in the hippocampus, an area critical for associative learning. AA's structural and functional imaging results suggest that in a literate person, a right-hemispheric network can provide an effective alternative route for learning of novel active vocabulary. Importantly, AA's previously undetected word learning ability translated directly into therapy, as she could use written input also to successfully re-learn and maintain familiar words that she had lost due to her left hemisphere lesion. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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