Prenatal screening and diagnosis of aneuploidy in multiple pregnancies.
Prenatal screening for aneuploidy has changed significantly over the last 30 years, from being age-based to maternal serum and ultrasound based techniques. Multiple pregnancies present particular challenges with regards to screening as serum-based screening techniques are influenced by all feti whil...
| Publicado en: | Best Practice & Research: Clinical Obstetrics & Gynaecology Vol. 28; no. 2; pp. 285 - 295 |
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| Autores principales: | , |
| Formato: | Journal Article |
| Publicado: |
Elsevier B.V.
2014 Feb
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107888872&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 107888872 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15216934 3AUJ jtl: Best Practice & Research: Clinical Obstetrics & Gynaecology issn: 15216934 maglogo: N pubinfo: dt: 2014 Feb vid: 28 iid: 2 pid: 467 pub: Elsevier B.V. place: New York, New York artinfo: ui: 107888872 2012485939 10.1016/j.bpobgyn.2013.12.010 NLM24485166 107888872 ppf: 285 ppct: 10 formats: tig: atl: Prenatal screening and diagnosis of aneuploidy in multiple pregnancies. aug: au: Gagnon, Alain Audibert, Francois affil: University of British Columbia, Vancouver, British Columbia, Canada. Electronic address: agagnon@cw.bc.ca. sug: subj: Aneuploidy Pregnancy, Multiple Prenatal Diagnosis Methods Amniocentesis Chorionic Villi Sampling Down Syndrome Diagnosis Female Pregnancy Ultrasonography, Prenatal Female ab: Prenatal screening for aneuploidy has changed significantly over the last 30 years, from being age-based to maternal serum and ultrasound based techniques. Multiple pregnancies present particular challenges with regards to screening as serum-based screening techniques are influenced by all feti while ultrasound-based techniques can be fetus specific. Tests currently available tend to not perform as well in multiple compared to singleton pregnancies. Considerations must be given to these variations when discussing and performing screening for aneuploidy in this situation. Prenatal invasive diagnosis techniques in multiple pregnancies bring their own challenges from a technical and counselling point of view, in particular with regards to sampling error, mapping and assignment of results and management of abnormal results. This review addresses these particular challenges and provides information to facilitate care. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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