The effect of computer-aided detection on radiologist performance in the detection of lung cancers previously missed on a chest radiograph.

Purpose: The purpose of the study was to determine whether computer-aided detection (CAD) can improve a radiologist's ability to detect lung cancers previously missed on a chest radiograph (CXR). Materials and Methods: Eighty-one cases of lung cancer previously missed on CXR were collected, along wi...

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Publicado en:Journal of Thoracic Imaging Vol. 28; no. 4; pp. 244 - 253
Autores principales: Kligerman, Seth, Cai, Ling, White, Charles S
Formato: research Journal Article
Publicado: Lippincott Williams & Wilkins 2013 Jul
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2013 Jul
      vid: 28
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      pub: Lippincott Williams & Wilkins
      place: Baltimore, Maryland
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        107906231
        107906231
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        2012165947
        10.1097/RTI.0b013e31826c29ec
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        107906231
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        atl: The effect of computer-aided detection on radiologist performance in the detection of lung cancers previously missed on a chest radiograph.
      aug:
        au:
          Kligerman, Seth
          Cai, Ling
          White, Charles S
        affil: Departments of *Diagnostic Radiology and Nuclear Medicine tBiostatistics, University of Maryland School of Medicine, Baltimore, MD.
      sug:
        subj:
          Clinical Competence
          Lung Neoplasms Radiography
          Radiographic Image Interpretation, Computer-Assisted
          Adult
          Aged
          Aged, 80 and Over
          Diagnostic Errors
          Female
          Image Processing, Computer Assisted
          Male
          Middle Age
          Adult: 19-44 years
          Aged: 65+ years
          Aged, 80 & over
          Middle Aged: 45-64 years
          Female
          Male
      ab: Purpose: The purpose of the study was to determine whether computer-aided detection (CAD) can improve a radiologist's ability to detect lung cancers previously missed on a chest radiograph (CXR). Materials and Methods: Eighty-one cases of lung cancer previously missed on CXR were collected, along with the CXRs of 215 age-matched and emphysema-matched controls without lung cancer. Tumor subtlety was scored from 1 (very subtle) to 5 (very obvious) by expert thoracic radiologists. All 297 CXRs were processed using a CAD system (OnGuard, Version 5.1 Riverain Medical, Miamisburg, OH) to create a set of 2 images for each patient, 1 with and 1 without CAD. Eleven general radiologists took part in a reader study. Each radiologist viewed the CXR without CAD and then the one with CAD for each patient sequentially. Areas of concern, if present, were marked. The degree of confidence in diagnosis was scored on a scale of 0 (no cancer) to 100 (definite) in succession for CXRs without CAD and then for those with CAD. Localization receiver operating characteristic analysis was used for evaluation of the observers' performance. Results: Of the 81 cancer cases, OnGuard correctly detected 40 tumors with a sensitivity of 49.4%. In the reader study, there was a significant increase in the area under the localization receiver operating characteristic curve with the aid of OnGuard, which increased from 0.38 to 0.43. Aggregate reader sensitivity improved significantly from 0.44 to 0.5 with the use of OnGuard. Conclusion: The use of OnGuard improves reader accuracy and sensitivity for the detection of lung cancers previously missed on CXR.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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