Cover Image
QR Code

Zollinger-Ellison syndrome: recent advances and controversies.

Purpose Of Review: To review the recent advances and current controversies in patients with Zollinger-Ellison syndrome (ZES).Recent Findings: Recent advances in the management of ZES include: improved understanding of the pathogenesis of gastrinoma and pancreatic neuroendocrine tumors, new prognosti...

Full description

Published in:Current Opinion in Gastroenterology Vol. 29; no. 6; pp. 650 - 662
Main Authors: Ito, Tetsuhide, Igarashi, Hisato, Jensen, Robert T
Format: review Journal Article
Published: Lippincott Williams & Wilkins Nov2013
Online Access:View this record in EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107914807&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 107914807
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        02671379
        IQT
      jtl: Current Opinion in Gastroenterology
      issn: 02671379
      maglogo: N
    pubinfo:
      dt: Nov2013
      vid: 29
      iid: 6
      pid: 433
      pub: Lippincott Williams & Wilkins
      place: Baltimore, Maryland
    artinfo:
      ui:
        107914807
        NLM24100728
        2012337640
        10.1097/MOG.0b013e328365efb1
        NLM24100728
        107914807
      ppf: 650
      ppct: 12
      formats:
      tig:
        atl: Zollinger-Ellison syndrome: recent advances and controversies.
      aug:
        au:
          Ito, Tetsuhide
          Igarashi, Hisato
          Jensen, Robert T
        affil: aDepartment of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Higashi-ku, Fukuoka, Japan bDigestive Diseases Branch, NIDDK, NIH, Bethesda, Maryland, USA.
      sug:
        subj:
          Zollinger-Ellison Syndrome Diagnosis
          Zollinger-Ellison Syndrome Therapy
          Diagnosis, Differential
          Gastric Acid
          Gastrinoma Diagnosis
          Gastrinoma
          Gastrinoma Surgery
          Pancreatic Neoplasms Diagnosis
          Pancreatic Neoplasms Surgery
      ab: Purpose Of Review: To review the recent advances and current controversies in patients with Zollinger-Ellison syndrome (ZES).Recent Findings: Recent advances in the management of ZES include: improved understanding of the pathogenesis of gastrinoma and pancreatic neuroendocrine tumors, new prognostic classification systems, new diagnostic algorithms, more sensitive localization studies, new treatment strategies including improved control of gastric acid secretion and role for surgery, and new approaches to patients with advanced disease. Controversies include: the best approach to a patient with hypergastrinemia suspected of possibly having ZES, the appropriate gastrin assay to use, the role of surgery in patients with ZES, especially those with multiple endocrine neoplasia type 1, and the precise order of therapeutic modalities in the treatment of patients with advanced disease.Summary: This review updates clinicians regarding important advances and controversies required to optimally diagnose and manage patients with ZES.
      pubtype: Academic Journal
      doctype:
        review
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N