Comparative effectiveness research designs: an analysis of terms and coverage in Medical Subject Headings (MeSH) and Emtree.

Objectives: We analyzed the extent to which comparative effectiveness research (CER) organizations share terms for designs, analyzed coverage of CER designs in Medical Subject Headings (MeSH) and Emtree, and explored whether scientists use CER design terms. Methods: We developed local terminologies...

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Published in:Journal of the Medical Library Association Vol. 101; no. 2; pp. 92 - 101
Main Authors: Bekhuis, Tanja, Demner-Fushman, Dina, Crowley, Rebecca
Format: research tables/charts Journal Article
Published: University of Pittsburgh, University Library System Apr2013
Online Access:View this record in EBSCOhost
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      dt: Apr2013
      vid: 101
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      pub: University of Pittsburgh, University Library System
      place: Pittsburgh, Pennsylvania
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        atl: Comparative effectiveness research designs: an analysis of terms and coverage in Medical Subject Headings (MeSH) and Emtree.
      aug:
        au:
          Bekhuis, Tanja
          Demner-Fushman, Dina
          Crowley, Rebecca
        affil: Assistant Professor, Department of Biomedical Informatics, School of Medicine, University of Pittsburgh, 5607 Baum Boulevard, Room 514, Pittsburgh, PA 15206
      sug:
        subj:
          Subject Headings
          Comparative Studies
          Medical Literature
          Medical Practice, Evidence-Based
          Study Design
          Human
          Vocabulary, Controlled
          Information Retrieval
          Funding Source
          Algorithms
          United States Agency for Healthcare Research and Quality
          Data Analysis Software
          Outcomes Research
          Health Services Research
          PubMed
      ab: Objectives: We analyzed the extent to which comparative effectiveness research (CER) organizations share terms for designs, analyzed coverage of CER designs in Medical Subject Headings (MeSH) and Emtree, and explored whether scientists use CER design terms. Methods: We developed local terminologies (LTs) and a CER design terminology by extracting terms in documents from five organizations. We defined coverage as the distribution over match type in MeSH and Emtree. We created a crosswalk by recording terms to which design terms mapped in both controlled vocabularies. We analyzed the hits for queries restricted to titles and abstracts to explore scientists' language. Results: Pairwise LT overlap ranged from 22.64% (12/53) to 75.61% (31/41). The CER design terminology (n=78 terms) consisted of terms for primary study designs and a few terms useful for evaluating evidence, such as opinion paper and systematic review. Patterns of coverage were similar in MeSH and Emtree (gamma=0.581, P=0.002). Conclusions: Stakeholder terminologies vary, and terms are inconsistently covered in MeSH and Emtree. The CER design terminology and crosswalk may be useful for expert searchers. For partially mapped terms, queries could consist of free text for modifiers such as nonrandomized or interrupted added to broad or related controlled terms.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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