An opportunistic infection associated with ruxolitinib, a novel janus kinase 1,2 inhibitor.

We report a case of Cryptococcus neoformans pneumonia in a patient taking ruxolitinib, a janus kinase 1,2 inhibitor approved for the treatment of myelofibrosis. We hypothesize that ruxolitinib contributed to this infection through its effects on cell-mediated immunity. Clinicians should be aware of...

Full description

Bibliographic Details
Published in:CHEST Vol. 143; no. 5; pp. 1478 - 1480
Main Authors: Wysham, Nicholas G., Sullivan, Donald R., Allada, Gopal
Format: case study Journal Article
Published: American College of Chest Physicians 2013 May
Online Access:View this record in EBSCOhost