Acute Electroencephalographic Effects From Repeated Olfactory Administration of Homeopathic Remedies in Individuals With Self-reported Chemical Sensitivity.
Background Homeopaths report that individuals with heightened self-reported environmental chemical intolerance (CI) exhibit increased reactivity to homeopathic remedies. Persons high in CI sensitize their electroencephalographic (EEG) alpha responses to repeated intermittent chemical exposures. Prim...
| Publicado en: | Alternative Therapies in Health & Medicine Vol. 19; no. 1; pp. 46 - 58 |
|---|---|
| Autores principales: | , , , , |
| Formato: | research randomized controlled trial Journal Article |
| Publicado: |
InnoVisions Professional Media
Jan/Feb2013
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108021939&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 108021939 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10786791 88C jtl: Alternative Therapies in Health & Medicine issn: 10786791 maglogo: N pubinfo: dt: Jan/Feb2013 vid: 19 iid: 1 pid: 65582 pub: InnoVisions Professional Media place: Eagan, Minnesota artinfo: ui: 108021939 108021939 2011910141 NLM23341426 108021939 ppf: 46 ppct: 12 formats: fmt: @attributes: type: P tig: atl: Acute Electroencephalographic Effects From Repeated Olfactory Administration of Homeopathic Remedies in Individuals With Self-reported Chemical Sensitivity. aug: au: Bell IR Brooks AJ Howerter A Jackson N Schwartz GE affil: Department of Family and Community Medicine, University of Arizona, AZ, USA. ibell@email.arizona.edu sug: subj: Electroencephalography Homeopathy Nosode Administration and Dosage Multiple Chemical Sensitivity Smell Drug Effects Administration, Intranasal Adult Double-Blind Studies Pilot Studies Female Human Male Plant Extracts Administration and Dosage Plants Self Report Sulfur Administration and Dosage Young Adult Adult: 19-44 years Female Male ab: Background Homeopaths report that individuals with heightened self-reported environmental chemical intolerance (CI) exhibit increased reactivity to homeopathic remedies. Persons high in CI sensitize their electroencephalographic (EEG) alpha responses to repeated intermittent chemical exposures. Primary Study Objective The present feasibility study explored interactions between CI and one of two specific homeopathic remedies over time (Sulphur or Pulsatilla nigricans [Pulsatilla]). Design This study used a two-arm, double-blind, placebo-controlled repeated measures design. Intervention Participants underwent a series of three once-weekly sessions during which they repeatedly sniffed one remedy (6c, 12c, 30c; one potency per week) matched to their Homeopathic Constitutional Type Questionnaire (CTQ) type and two solvent controls (distilled water and a waterethanol [95%] solution). Within sessions, remedies and control solvents were administered via 2-second sniffs (eight sniffs of each of four different succussion levels per potency, in randomized order). Participants Participants were college student volunteers (N = 96, ages 18-30, both sexes), screened for good health and relatively elevated Sulphur or Pulsatilla symptom pattern scores on the Homeopathic Constitutional Type Questionnaire (CTQ). Participants also completed a validated trait CI scale. Primary Outcome Measures Average 19-lead relative EEG alpha power (alpha 1 8-10 Hz; alpha 2 10-12 Hz). Results Trait CI interacted significantly with time factors for each remedy (both over visit weeks and over sniff cycles during sessions). The patterns were nonlinear and differed between the two remedies. Individuals high in CI showed greater variability over time in remedy EEG alpha effects than did those low in CI. Conclusion The data suggest that CI, with an underlying susceptibility to time-dependent sensitization and oscillatory responses, could contribute to nonlinear dose-response patterns and inconsistent reproducibility of homeopathic clinical care and research. (Altern Ther Health Med. 2013;19(1):46-57.). pubtype: Academic Journal doctype: research randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|