Awareness of disease state without explicit knowledge of memory failure in transient global amnesia.
INTRODUCTION: Transient global amnesia (TGA) is a syndrome characterised by the rapid onset of antero- and retrograde amnesia, accompanied by temporal disorientation and iterative questioning. It is now established that the acute phase is associated with a raised level of anxiety and a depressed moo...
| Publicado en: | Cortex: A Journal Devoted to the Study of the Nervous System & Behavior Vol. 48; no. 8; pp. 1079 - 1085 |
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| Autores principales: | , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Masson SPA
2012 Sep
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108065820&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 108065820 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00109452 GMP jtl: Cortex: A Journal Devoted to the Study of the Nervous System & Behavior issn: 00109452 maglogo: N pubinfo: dt: 2012 Sep vid: 48 iid: 8 pid: 12473 pub: Masson SPA artinfo: ui: 108065820 108065820 2011612250 10.1016/j.cortex.2012.02.003 NLM22424958 108065820 ppf: 1079 ppct: 6 formats: tig: atl: Awareness of disease state without explicit knowledge of memory failure in transient global amnesia. aug: au: Hainselin M Quinette P Desgranges B Martinaud O de La Sayette V Hannequin D Viader F Eustache F affil: Inserm, U1077, Caen, France; Université de Caen Basse-Normandie, UMR-S1077, Caen, France; Ecole Pratique des Hautes Etudes, UMR-S1077, Caen, France; CHU de Caen, U1077, France. sug: subj: Amnesia Physiopathology Memory Disorders Physiopathology Aged Amnesia Psychosocial Factors Anxiety Psychosocial Factors Cognition Depression Psychosocial Factors Emotions Female Human Male Memory Disorders Psychosocial Factors Middle Age Neuropsychological Tests Aged: 65+ years Middle Aged: 45-64 years Female Male ab: INTRODUCTION: Transient global amnesia (TGA) is a syndrome characterised by the rapid onset of antero- and retrograde amnesia, accompanied by temporal disorientation and iterative questioning. It is now established that the acute phase is associated with a raised level of anxiety and a depressed mood. We conducted a thorough investigation of patients' perceptions of their disease state, focusing on the links between their lack of explicit knowledge of amnesia during the acute phase and their emotional experience. METHOD: Explicit knowledge of memory deficits was assessed during TGA by means of an original scale inspired by Bisiach et al. (1986) and self-reported scales measuring patients' perceptions of their current memory and their cognitive and behavioural functioning. At the same time, we probed the patients' emotional experience (sources of worry, and levels of worry, anxiety and depression) via questionnaires. Data were collected from 20 patients in the acute phase, 16 in the peri-acute phase, 16 who were assessed the day after the episode and 14 healthy controls. Each patient underwent a follow-up examination 2months later. RESULTS: Patients in the acute phase displayed a lack of explicit knowledge of their amnesia and overestimated their memory performances. They also expressed higher levels of worry and anxiety than controls, and a more depressed mood. CONCLUSIONS: Although they were aware of their disease state, the TGA patients were unable to identify the nature of their memory deficits and overestimated their memory performances. These memory misperceptions and the inability to acknowledge memory failure occurred concomitantly with changes in the patients' emotional state. This particular pattern of awareness could be regarded as a reaction to the suddenness and massiveness of the amnesia. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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