Candidal endocarditis presenting with bilateral lower limb ischemia.
The incidence of fungal endocarditis is increasing. While the pathogenic mechanisms are not fully understood, infection is associated with underlying heart disease and is most often attributable to Candida species. Candidal endocarditis complications include heart damage, inflammation, and emboli wi...
| Publicado en: | Clinical Laboratory Science Vol. 25; no. 3; pp. 130 - 135 |
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| Autores principales: | , |
| Formato: | case study tables/charts Journal Article |
| Publicado: |
American Society for Clinical Laboratory Science
Summer2012
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108148430&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 108148430 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 0894959X IKL jtl: Clinical Laboratory Science issn: 0894959X maglogo: N pubinfo: dt: Summer2012 vid: 25 iid: 3 pid: 13703 pub: American Society for Clinical Laboratory Science place: Dundee, Michigan artinfo: ui: 108148430 2011667283 10.29074/ascls.25.3.130 NLM22953512 108148430 ppf: 130 ppct: 5 formats: fmt: @attributes: type: P tig: atl: Candidal endocarditis presenting with bilateral lower limb ischemia. aug: au: Card, Lauren Lofland, Denene affil: Armstrong Atlantic State University, Department of Medical Technology, 11935 Abercorn St., Savannah, GA sug: subj: Aorta Pathology Candidiasis Endocarditis Microbiology Adult Candidiasis Diagnosis Candidiasis Drug Therapy Candidiasis Etiology Comorbidity Female Microbiological Techniques Adult: 19-44 years Female ab: The incidence of fungal endocarditis is increasing. While the pathogenic mechanisms are not fully understood, infection is associated with underlying heart disease and is most often attributable to Candida species. Candidal endocarditis complications include heart damage, inflammation, and emboli with resulting ischemia and tissue death. Candidal endocarditis is difficult to diagnose as blood cultures are often negative. Treatment includes surgical intervention and antifungal therapy. This case study describes a 41-year-old female complaining of acute onset of pain with numbness and tingling in both lower extremities. Prior history was significant for mycotic valve aneurysm and replacement secondary to culture-negative endocarditis. Evidence of limb-threatening ischemia led to a bilateral thrombectomy. During the thrombectomy white debris, later identified as Candida albicans, was encountered. A transesophogeal echocardiogram revealed a pedunculated mass which was determined to be the source of infection. The patient was placed on micafungin and voriconazole and discharged with a diagnosis of C albicans fungal infection with descending aorta fungal mass. This case study illustrates an unusual presentation of candidal endocarditis with discussion of disease epidemiology, pathogenesis, diagnosis, and treatment. pubtype: Academic Journal doctype: case study tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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