Pattern and motion-related visual-evoked potentials in neuroborreliosis: follow-up study.

SUMMARY: Visual-evoked potentials (VEPs) were used for objective testing of visual functions during treatment courses of Lyme neuroborreliosis (LNB) in adult patients in the Czech Republic. In 30 LNB patients with originally delayed VEP latencies, pattern-reversal (R-VEP) and motion onset (M-VEP) VE...

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Published in:Journal of Clinical Neurophysiology Vol. 29; no. 2; pp. 174 - 181
Main Authors: Szanyi J, Kubová Z, Kremlácek J, Langrová J, Vít F, Kuba M, Plísek S
Format: research Journal Article
Published: Lippincott Williams & Wilkins 2012 Apr
Online Access:View this record in EBSCOhost
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      dt: 2012 Apr
      vid: 29
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      pub: Lippincott Williams & Wilkins
      place: Baltimore, Maryland
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        108174927
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        10.1097/wnp.0b013e31824e1013
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        atl: Pattern and motion-related visual-evoked potentials in neuroborreliosis: follow-up study.
      aug:
        au:
          Szanyi J
          Kubová Z
          Kremlácek J
          Langrová J
          Vít F
          Kuba M
          Plísek S
        affil: Department of Pathophysiology, Faculty of Medicine in Hradec Králové, Charles University tDepartment of Infectious diseases, Faculty Hospital in Hradec Králové, Czech Republic.
      sug:
        subj:
          Evoked Potentials, Visual Physiology
          Lyme Neuroborreliosis Physiopathology
          Adolescence
          Adult
          Aged
          Female
          Prospective Studies
          Human
          Lyme Neuroborreliosis Complications
          Male
          Middle Age
          Vision Disorders Etiology
          Vision Disorders Physiopathology
          Young Adult
          Adolescent: 13-18 years
          Adult: 19-44 years
          Aged: 65+ years
          Middle Aged: 45-64 years
          Female
          Male
      ab: SUMMARY: Visual-evoked potentials (VEPs) were used for objective testing of visual functions during treatment courses of Lyme neuroborreliosis (LNB) in adult patients in the Czech Republic. In 30 LNB patients with originally delayed VEP latencies, pattern-reversal (R-VEP) and motion onset (M-VEP) VEPs were repeatedly examined within 1 to 8 years. Six patients had Lyme optic neuritis (ON), five of them displayed prolonged latencies in both R-VEPs and M-VEPs, and one had only abnormal R-VEPs. The VEP recovery to normal latency values was in three of them. In the group of 24 LNB patients without ON, 14 patients displayed prolonged latencies only to motion stimuli, and 10 patients had abnormal latencies in both R-VEPs and M-VEPs. During the follow-up period, 7 patients displayed shortening to normal latencies. In 5 patients, VEPs latencies improved only partially, and in the remaining 12 patients, VEPs did not improve at all. This study provides objective evidence that in LNB, most of the patients without clinically manifesting ON display optic pathway involvement-predominantly magnocellular system/dorsal stream function changes. In patients with ON, however, mainly the parvocellular system is affected. About half of the patients without ON improved with a relatively long-time course of latency shortening.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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