Cryptogenic hepatitis: a case study in autoantibody negative autoimmune hepatitis.
A 76 year old white-female initially presented with signs and symptoms of acute hepatitis. While liver function tests were elevated, viral hepatitis and autoimmune hepatitis panels were negative. The patient was subsequently discharged on the 4th day of hospitalization when her condition appeared to...
| Publicado en: | Clinical Laboratory Science Vol. 24; no. 4; pp. 196 - 202 |
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| Autores principales: | , |
| Formato: | case study pictorial tables/charts Journal Article |
| Publicado: |
American Society for Clinical Laboratory Science
Fall2011
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108210076&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 108210076 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 0894959X IKL jtl: Clinical Laboratory Science issn: 0894959X maglogo: N pubinfo: dt: Fall2011 vid: 24 iid: 4 pid: 13703 pub: American Society for Clinical Laboratory Science place: Dundee, Michigan artinfo: ui: 108210076 2011396930 10.29074/ascls.24.4.196 NLM22288215 108210076 ppf: 196 ppct: 6 formats: fmt: @attributes: type: P tig: atl: Cryptogenic hepatitis: a case study in autoantibody negative autoimmune hepatitis. aug: au: Gacad, Vincent Waller, Kathy affil: The Ohio State University, Columbus, OH sug: subj: Autoimmune Diseases Diagnosis Hepatitis Diagnosis Acute Disease Aged Autoimmune Diseases Drug Therapy Autoimmune Diseases Etiology Autoimmune Diseases Symptoms Female Hepatitis Drug Therapy Hepatitis Etiology Hepatitis Symptoms Liver Function Tests Aged: 65+ years Female ab: A 76 year old white-female initially presented with signs and symptoms of acute hepatitis. While liver function tests were elevated, viral hepatitis and autoimmune hepatitis panels were negative. The patient was subsequently discharged on the 4th day of hospitalization when her condition appeared to stabilize. Four weeks later she was readmitted to the hospital, this time with signs and symptoms of acute liver failure with ascites, confusion, and jaundice. A liver biopsy was performed with pathology suggestive of an autoimmune etiology despite the negative autoimmune antibody panel. She was diagnosed with cryptogenic autoimmune hepatitis. The patient was placed on intravenous steroids and later oral prednisone that resulted in the resolution of the liver failure and disappearance of the encephalopathy along with a downward trend of the liver enzymes, bilirubin and the prothrombin time. One year later, the liver enzymes had normalized and the autoimmune disease remained in remission with maintenance medications consisting oflow dose prednisone and azathioprine. pubtype: Academic Journal doctype: case study pictorial tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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