The performance of two automatic servo-ventilation devices in the treatment of central sleep apnea.
INTRODUCTION: This study was conducted to evaluate the therapeutic performance of a new auto Servo Ventilation device (Philips Respironics autoSV Advanced) for the treatment of complex central sleep apnea (CompSA). The features of autoSV Advanced include an automatic expiratory pressure (EPAP) adjus...
| Publicado en: | Sleep Vol. 34; no. 12; pp. 1693 - 1699 |
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| Autores principales: | , , , , , |
| Formato: | research randomized controlled trial Journal Article |
| Publicado: |
Oxford University Press / USA
2011
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108217203&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 108217203 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01618105 2EI jtl: Sleep issn: 01618105 maglogo: N pubinfo: dt: 2011 vid: 34 iid: 12 pid: 622 pub: Oxford University Press / USA artinfo: ui: 108217203 108217203 2011416650 NLM22131607 PMC3208847 108217203 ppf: 1693 ppct: 6 formats: tig: atl: The performance of two automatic servo-ventilation devices in the treatment of central sleep apnea. aug: au: Javaheri, Shahrokh Goetting, Mark G Khayat, Rami Wylie, Paul E Goodwin, James L Parthasarathy, Sairam sug: subj: Positive End-Expiratory Pressure Equipment and Supplies Sleep Apnea, Central Therapy Continuous Positive Airway Pressure Expiration Physiology Female Human Male Middle Age Polysomnography Positive End-Expiratory Pressure Methods Randomized Controlled Trials Sleep Apnea, Central Physiopathology Middle Aged: 45-64 years Female Male ab: INTRODUCTION: This study was conducted to evaluate the therapeutic performance of a new auto Servo Ventilation device (Philips Respironics autoSV Advanced) for the treatment of complex central sleep apnea (CompSA). The features of autoSV Advanced include an automatic expiratory pressure (EPAP) adjustment, an advanced algorithm for distinguishing open versus obstructed airway apnea, a modified auto backup rate which is proportional to subject's baseline breathing rate, and a variable inspiratory support. Our primary aim was to compare the performance of the advanced servo-ventilator (BiPAP autoSV Advanced) with conventional servo-ventilator (BiPAP autoSV) in treating central sleep apnea (CSA). STUDY DESIGN: A prospective, multicenter, randomized, controlled trial. SETTING: Five sleep laboratories in the United States. PARTICIPANTS: Thirty-seven participants were included. MEASUREMENTS AND RESULTS: All subjects had full night polysomnography (PSG) followed by a second night continuous positive airway pressure (CPAP) titration. All had a central apnea index >= 5 per hour of sleep on CPAP. Subjects were randomly assigned to 2 full-night PSGs while treated with either the previously marketed autoSV, or the new autoSV Advanced device. The 2 randomized sleep studies were blindly scored centrally. Across the 4 nights (PSG, CPAP, autoSV, and autoSV Advanced), the mean ± 1 SD apnea hypopnea indices were 53 ± 23, 35 ± 20, 10 ± 10, and 6 ± 6, respectively; indices for CSA were 16 ± 19, 19 ± 18, 3 ± 4, and 0.6 ± 1. AutoSV Advanced was more effective than other modes in correcting sleep related breathing disorders. CONCLUSIONS: BiPAP autoSV Advanced was more effective than conventional BiPAP autoSV in the treatment of sleep disordered breathing in patients with CSA. CITATION: Javaheri S; Goetting MG; Khayat R; Wylie PE; Goodwin JL; Parthasarathy S. The performance of two automatic servo-ventilation devices in the treatment of central sleep apnea. SLEEP 2011;34(12):1693-1698. pubtype: Academic Journal doctype: research randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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