Lung nodules: improved detection with software that suppresses the rib and clavicle on chest radiographs.
Purpose: To demonstrate possible superiority in the performance of a radiologist who is tasked with detecting actionable nodules and aided by the bone suppression and soft-tissue visualization algorithm of a new software program that produces a modified image by suppressing the ribs and clavicles, f...
| Publicado en: | Radiology Vol. 260; no. 1; pp. 265 - 274 |
|---|---|
| Autores principales: | , , , , , , , |
| Formato: | research randomized controlled trial Journal Article |
| Publicado: |
Wolters Kluwer Health
2011 Jul
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108233273&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 108233273 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00338419 0IQ jtl: Radiology issn: 00338419 maglogo: N pubinfo: dt: 2011 Jul vid: 260 iid: 1 pid: 79357 pub: Wolters Kluwer Health place: New York, New York artinfo: ui: 108233273 108233273 NLM21493789 2011187083 10.1148/radiol.11100153 NLM21493789 108233273 ppf: 265 ppct: 9 formats: tig: atl: Lung nodules: improved detection with software that suppresses the rib and clavicle on chest radiographs. aug: au: Freedman MT Lo SC Seibel JC Bromley CM Freedman, Matthew Thomas Lo, Shih-Chung Benedict Seibel, John C Bromley, Christina M affil: Lombardi Comprehensive Cancer Center and Department of Oncology, Georgetown University Medical Center, 3800 Reservoir Rd NW, Room S150, Washington, DC 20057-1465, USA. Freedmmt@georgetown .edu sug: subj: Clavicle Radiography Lung Neoplasms Radiography Radiographic Image Enhancement Methods Radiography, Thoracic Methods Ribs Radiography Software Aged Algorithms Female Human Male Middle Age Randomized Controlled Trials Reproducibility of Results Sensitivity and Specificity Aged: 65+ years Middle Aged: 45-64 years Female Male ab: Purpose: To demonstrate possible superiority in the performance of a radiologist who is tasked with detecting actionable nodules and aided by the bone suppression and soft-tissue visualization algorithm of a new software program that produces a modified image by suppressing the ribs and clavicles, filtering noise, and equalizing the contrast in the area of the lungs. Materials and Methods: The study and use of anonymized and deidentified data received approval from the MedStar-Georgetown University Oncology Institutional Review Board. Informed consent was obtained from 15 study radiologists. The study radiologists participated as observers in a reader study of 368 patients in an approximately 2:1 cancer-free-to-cancer ratio. The localized receiver operating characteristic (LROC) method was used for analyses. Images were rerandomized for each radiologist. Each patient image was sequentially read, first with the standard radiograph and then with the software-aided image. Normal studies were confirmed with computed tomography (CT), follow-up, and/or panel consensus. Results: Each reader and the combined scores of the 15 readers showed improvement. The area under the combined LROC curve increased significantly from 0.460 unaided to 0.558 aided by visualization software (P = .0001). When measured according to the reader's indication that a case should be sent or not sent for CT or biopsy, sensitivity for cancer detection increased from 49.5% unaided to 66.3% aided by software (P < .0001); specificity decreased from 96.1% to 91.8% (P = .004). Seventy-four percent of the aided detections occurred in cancers with 70% or greater overlap of the bone and the nodule. Conclusion: The radiologists using visualization software significantly increased their detection of lung cancers and benign nodules. pubtype: Academic Journal doctype: research randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|