A Novel Noninvasive Method for Measuring Fatigability of the Quadriceps Muscle in Noncooperating Healthy Subjects.

Background. Critical illness is associated with muscle weakness leading to long-term functional limitations. Objectives. To assess the reliability of a novel method for evaluating fatigability of the quadriceps muscle in noncooperating healthy subjects. Methods. On two occasions, separated by seven...

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Publicado en:BioMed Research International Vol. 2015; pp. 1 - 8
Autores principales: Poulsen, Jesper B., Rose, Martin H., Møller, Kirsten, Perner, Anders, Jensen, Bente R.
Formato: pictorial research Journal Article
Publicado: Wiley-Blackwell 7/21/2015
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 7/21/2015
      vid: 2015
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2015/193493
        109030925
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        atl: A Novel Noninvasive Method for Measuring Fatigability of the Quadriceps Muscle in Noncooperating Healthy Subjects.
      aug:
        au:
          Poulsen, Jesper B.
          Rose, Martin H.
          Møller, Kirsten
          Perner, Anders
          Jensen, Bente R.
        affil: Department of Intensive Care, Rigshospitalet, Copenhagen University Hospital, 2100 Copenhagen OE, Denmark
      sug:
        subj:
          Fatigue Diagnosis
          Quadriceps Muscles
          Noninvasive Procedures
          Human
          Funding Source
          Critical Illness
          Muscle Weakness
          Torque
          Regression
          Intraclass Correlation Coefficient
          Descriptive Statistics
          Confidence Intervals
          Male
          Adult
          Body Height
          Body Weight
          Goodness of Fit Chi Square Test
          Data Analysis Software
          Adult: 19-44 years
          Male
      ab: Background. Critical illness is associated with muscle weakness leading to long-term functional limitations. Objectives. To assess the reliability of a novel method for evaluating fatigability of the quadriceps muscle in noncooperating healthy subjects. Methods. On two occasions, separated by seven days, nonvoluntary isometric contractions (twitch and tetanic) of the quadriceps femoris muscle evoked by transcutaneous electrical muscle stimulation were recorded in twelve healthy adults. For tetanic contractions, the Fatigue Index (ratio of peak torque values) and the slope of the regression line of peak torque values were primary outcome measures. For twitch contractions, maximum peak torque and rise time were calculated. Relative (intraclass correlation, ICC3.1) and absolute (standard error of measurement, SEM) reliability were assessed and minimum detectable change was calculated using a 95% confidence interval (MDC95%). Results. The Fatigue Index (ICC3.1, 0.84; MDC95%, 0.12) and the slope of the regression line (ICC3.1, 0.99; MDC95%, 0.03) showed substantial relative and absolute reliability during the first 15 and 30 contractions, respectively. Conclusion. This method for assessing fatigability of the quadriceps muscle produces reliable results in healthy subjects and may provide valuable data on quantitative changes in muscle working capacity and treatment effects in patients who are incapable of producing voluntary muscle contractions.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        Journal Article
      ougenre: Article
    language: English
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