The Interplay between Cyclic AMP, MAPK, and NF-κB Pathways in Response to Proinflammatory Signals in Microglia.

Cyclic AMP is an important intracellular regulator of microglial cell homeostasis and its negative perturbation through proinflammatory signaling results in microglial cell activation. Though cytokines, TNF-α and IL-1β, decrease intracellular cyclic AMP, the mechanism by which this occurs is poorly...

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Bibliographic Details

Published in:	BioMed Research International Vol. 2015; pp. 1 - 19
Main Authors:	Ghosh, Mousumi, Aguirre, Vladimir, Wai, Khine, Felfly, Hady, Dietrich, W. Dalton, Pearse, Damien D.
Format:	pictorial research tables/charts Journal Article
Published:	Wiley-Blackwell 2/5/2015
Online Access:	View this record in EBSCOhost