Predictors of Mortality for Nursing Home-Acquired Pneumonia: A Systematic Review.

Background. Current risk stratification tools, primarily used for CAP, are suboptimal in predicting nursing home acquired pneumonia (NHAP) outcome and mortality. We conducted a systematic review to evaluate current evidence on the usefulness of proposed predictors of NHAP mortality. Methods. PubMed...

Descripción completa

Detalles Bibliográficos
Publicado en:BioMed Research International Vol. 2015; pp. 1 - 12
Autores principales: Dhawan, Naveen, Pandya, Naushira, Khalili, Michael, Bautista, Manuel, Duggal, Anurag, Bahl, Jaya, Gupta, Vineet
Formato: meta analysis research systematic review tables/charts Journal Article
Publicado: Wiley-Blackwell 3/2/2015
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109273531&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 109273531
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        23146133
        FT2T
      jtl: BioMed Research International
      issn: 23146133
      maglogo: N
    pubinfo:
      dt: 3/2/2015
      vid: 2015
      pid: 480
      pub: Wiley-Blackwell
      place: Malden, Massachusetts
    artinfo:
      ui:
        109273531
        109273531
        109273531
        10.1155/2015/285983
        109273531
      ppf: 1
      ppct: 11
      formats:
        fmt:
          @attributes:
            type: P
      tig:
        atl: Predictors of Mortality for Nursing Home-Acquired Pneumonia: A Systematic Review.
      aug:
        au:
          Dhawan, Naveen
          Pandya, Naushira
          Khalili, Michael
          Bautista, Manuel
          Duggal, Anurag
          Bahl, Jaya
          Gupta, Vineet
        affil: Nova Southeastern University Health Sciences Division, Fort Lauderdale, FL 33314, USA
      sug:
        subj:
          Pneumonia Risk Factors
          Nursing Home Residents
          Mortality Risk Factors
          Human
          Systematic Review
          Meta Analysis
          Medline
          Embase
          CINAHL Database
          Biological Markers Therapeutic Use
      ab: Background. Current risk stratification tools, primarily used for CAP, are suboptimal in predicting nursing home acquired pneumonia (NHAP) outcome and mortality. We conducted a systematic review to evaluate current evidence on the usefulness of proposed predictors of NHAP mortality. Methods. PubMed (MEDLINE), EMBASE, and CINAHL databases were searched for articles published in English between January 1978 and January 2014. The literature search elicited a total of 666 references; 580 were excluded and 20 articles met the inclusion criteria for the final analysis. Results. More studies supported the Pneumonia Severity Index (PSI) as a superior predictor of NHAP severity. Fewer studies suggested CURB-65 and SOAR (especially for the need of ICU care) as useful predictors for NHAP mortality. There is weak evidence for biomarkers like C-reactive protein and copeptin as prognostic tools. Conclusion. The evidence supports the use of PSI as the best available indicator while CURB-65 may be an alternative prognostic indicator for NHAP mortality. Overall, due to the paucity of information, biomarkers may not be as effective in this role. Larger prospective studies are needed to establish the most effective predictor(s) or combination scheme to help clinicians in decision-making related to NHAP mortality.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N