PMMA Third-Body Wear after Unicondylar Knee Arthroplasty Decuples the UHMWPE Wear Particle Generation In Vitro.

Introduction. Overlooked polymethylmethacrylate after unicondylar knee arthroplasty can be a potential problem, since this might influence the generated wear particle size and morphology. The aim of this study was the analysis of polyethylene wear in a knee wear simulator for changes in size, morpho...

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Publicado en:BioMed Research International Vol. 2015; pp. 1 - 8
Autores principales: Paulus, Alexander Christoph, Franke, Manja, Kraxenberger, Michael, Schröder, Christian, Jansson, Volkmar, Utzschneider, Sandra
Formato: equations & formulas pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell 3/19/2015
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 3/19/2015
      vid: 2015
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        109273693
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        10.1155/2015/575849
        109273693
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        atl: PMMA Third-Body Wear after Unicondylar Knee Arthroplasty Decuples the UHMWPE Wear Particle Generation In Vitro.
      aug:
        au:
          Paulus, Alexander Christoph
          Franke, Manja
          Kraxenberger, Michael
          Schröder, Christian
          Jansson, Volkmar
          Utzschneider, Sandra
        affil: Department of Orthopedic Surgery, University Hospital of Munich (LMU), Campus Großhadern, Marchioninistraße 15, 81377 Munich, Germany
      sug:
        subj:
          Arthroplasty, Knee, Unicompartmental
          Methylmethacrylates Adverse Effects
          Particle Size
          Joint Prosthesis
          Simulations
          Materials Testing
          Microscopy, Electron, Scanning
          Particle Size Evaluation
          Prosthesis Failure Etiology
          Bone and Bones
          In Vitro Studies
          Kruskal-Wallis Test
          One-Way Analysis of Variance
          P-Value
          Funding Source
      ab: Introduction. Overlooked polymethylmethacrylate after unicondylar knee arthroplasty can be a potential problem, since this might influence the generated wear particle size and morphology. The aim of this study was the analysis of polyethylene wear in a knee wear simulator for changes in size, morphology, and particle number after the addition of third-bodies. Material and Methods. Fixed bearing unicondylar knee prostheses (UKA) were tested in a knee simulator for 5.0 million cycles. Following bone particles were added for 1.5 million cycles, followed by 1.5 million cycles with PMMA particles. A particle analysis by scanning electron microscopy of the lubricant after the cycles was performed. Size and morphology of the generated wear were characterized. Further, the number of particles per 1 million cycles was calculated for each group. Results. The particles of all groups were similar in size and shape. The number of particles in the PMMA group showed 10-fold higher values than in the bone and control group (PMMA: 10.251×1012; bone: 1.145×1012; control: 1.804 × 1012). Conclusion. The addition of bone or PMMA particles in terms of a third-body wear results in no change of particle size and morphology. PMMA third-bodies generated tenfold elevated particle numbers. This could favor an early aseptic loosening.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        pictorial
        research
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        Journal Article
      ougenre: Article
    language: English
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