Design, Materials, and Mechanobiology of Biodegradable Scaffolds for Bone Tissue Engineering.

A review about design, manufacture, and mechanobiology of biodegradable scaffolds for bone tissue engineering is given. First, fundamental aspects about bone tissue engineering and considerations related to scaffold design are established. Second, issues related to scaffold biomaterials and manufact...

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Bibliographic Details
Published in:BioMed Research International Vol. 2015; pp. 1 - 22
Main Authors: Velasco, Marco A., Narváez-Tovar, Carlos A., Garzón-Alvarado, Diego A.
Format: equations & formulas review tables/charts Journal Article
Published: Wiley-Blackwell 3/26/2015
Online Access:View this record in EBSCOhost
Description
Summary:A review about design, manufacture, and mechanobiology of biodegradable scaffolds for bone tissue engineering is given. First, fundamental aspects about bone tissue engineering and considerations related to scaffold design are established. Second, issues related to scaffold biomaterials and manufacturing processes are discussed. Finally, mechanobiology of bone tissue and computational models developed for simulating how bone healing occurs inside a scaffold are described.