Relationship between Hyperuricemia and Haar-Like Features on Tongue Images.

Objective. To investigate differences in tongue images of subjects with and without hyperuricemia. Materials and Methods. This population-based case-control study was performed in 2012-2013. We collected data from 46 case subjects with hyperuricemia and 46 control subjects, including results of bioc...

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Publicado en:BioMed Research International Vol. 2015; pp. 1 - 11
Autores principales: Cui, Yan, Liao, Shizhong, Wang, Hongwu, Liu, Hongyu, Wang, Wenhua, Yin, Liqun
Formato: equations & formulas pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell 4/15/2015
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 4/15/2015
      vid: 2015
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2015/363216
        109273942
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        atl: Relationship between Hyperuricemia and Haar-Like Features on Tongue Images.
      aug:
        au:
          Cui, Yan
          Liao, Shizhong
          Wang, Hongwu
          Liu, Hongyu
          Wang, Wenhua
          Yin, Liqun
        affil: School of Computer Science and Technology, Tianjin University, 92 Weijin Road, Nankai District, Tianjin 300072, China
      sug:
        subj:
          Hyperuricemia Pathology
          Tongue Pathology
          Hyperuricemia Diagnosis
          Human
          Case Studies
          ROC Curve
          Sensitivity and Specificity
          China
          Male
          Female
          T-Tests
          Image Processing, Computer Assisted
          Data Analysis Software
          Adult
          Middle Age
          Aged
          Aged, 80 and Over
          Funding Source
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
          Male
          Female
      ab: Objective. To investigate differences in tongue images of subjects with and without hyperuricemia. Materials and Methods. This population-based case-control study was performed in 2012-2013. We collected data from 46 case subjects with hyperuricemia and 46 control subjects, including results of biochemical examinations and tongue images. Symmetrical Haar-like features based on integral images were extracted from tongue images. T-tests were performed to determine the ability of extracted features to distinguish between the case and control groups. We first selected features using the common criterion P<0.05, then conducted further examination of feature characteristics and feature selection using means and standard deviations of distributions in the case and control groups. Results. A total of 115,683 features were selected using the criterion P<0.05. The maximum area under the receiver operating characteristic curve (AUC) of these features was 0.877. The sensitivity of the feature with the maximum AUC value was 0.800 and specificity was 0.826 when the Youden index was maximized. Features that performed well were concentrated in the tongue root region. Conclusions. Symmetrical Haar-like features enabled discrimination of subjects with and without hyperuricemia in our sample. The locations of these discriminative features were in agreement with the interpretation of tongue appearance in traditional Chinese and Western medicine.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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