The R21C Mutation in Cardiac Troponin I Imposes Differences in Contractile Force Generation between the Left and Right Ventricles of Knock-In Mice.

We investigated the effect of the hypertrophic cardiomyopathy-linked R21C (arginine to cysteine) mutation in human cardiac troponin I (cTnI) on the contractile properties and myofilament protein phosphorylation in papillary muscle preparations from left (LV) and right (RV) ventricles of homozygous R...

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Publicado en:BioMed Research International Vol. 2015; pp. 1 - 10
Autores principales: Liang, Jingsheng, Kazmierczak, Katarzyna, Rojas, Ana I., Wang, Yingcai, Szczesna-Cordary, Danuta
Formato: pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell 4/16/2015
Acceso en línea:Ver este registro en EBSCOhost