Association between Arsenic Exposure and Diabetes: A Meta-Analysis.
Studies on the association between arsenic exposure and diabetes mellitus (DM) yielded inconsistent results. Epidemiologic data on the associations between arsenic exposures via inhalation and DM are limited. Therefore, we conducted a meta-analysis to evaluate the risk of DM associated with arsenic...
| Publicado en: | BioMed Research International Vol. 2015; pp. 1 - 11 |
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| Autores principales: | , , |
| Formato: | research systematic review Journal Article |
| Publicado: |
Wiley-Blackwell
4/27/2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109274030&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 109274030 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 23146133 FT2T jtl: BioMed Research International issn: 23146133 maglogo: N pubinfo: dt: 4/27/2015 vid: 2015 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 109274030 109274030 109274030 10.1155/2015/368087 109274030 ppf: 1 ppct: 10 formats: fmt: @attributes: type: P tig: atl: Association between Arsenic Exposure and Diabetes: A Meta-Analysis. aug: au: Sung, Tzu-Ching Huang, Jhih-Wei Guo, How-Ran affil: Department of Health Care Management, University of Kang Ning, 188 Anjhong Road, Section 5, Tainan 70970, Taiwan sug: subj: Arsenic Administration and Dosage Diabetes Mellitus Diagnosis Human Taiwan Environmental Exposure Arsenic Adverse Effects Drug Evaluation Glucose Tolerance Test Diabetes Mellitus Physiopathology Data Analysis Odds Ratio Confidence Intervals Funding Source Meta Analysis ab: Studies on the association between arsenic exposure and diabetes mellitus (DM) yielded inconsistent results. Epidemiologic data on the associations between arsenic exposures via inhalation and DM are limited. Therefore, we conducted a meta-analysis to evaluate the risk of DM associated with arsenic exposure. We searched the related literature through a systematic approach and analyzed the data according to the exposure route (inhalation and ingestion). We used random-effect models to estimate the summary relative risks (RRs) for DM associated with arsenic exposure and used I2 statistics to assess the heterogeneity of studies. We identified 38 relevant studies, of which the 32 on the ingestion route showed a significant association between arsenic exposure and DM (RR = 1.57; 95% CI 1.27–1.93). Focusing on the 24 studies in which the diagnosis of DM was confirmed using laboratory tests or medical records, we found that the summary RR was 1.71 (95% CI 1.32–2.23), very close to the overall estimates. We concluded that ingested arsenic is associated with the development of DM, but the heterogeneity among the studies may affect the results. pubtype: Academic Journal doctype: meta analysis research systematic review Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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