Diffusion and Persistence of Multidrug Resistant Salmonella Typhimurium Strains Phage Type DT120 in Southern Italy.

Sixty-two multidrug resistant Salmonella enterica serovar Typhimurium strains isolated from 255 clinical strains collected in Southern Italy in 2006–2008 were characterised for antimicrobial resistance genes, pulsotype, and phage type. Most strains (83.9%) were resistant to ampicillin, chloramphenic...

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Publicado en:BioMed Research International Vol. 2015; pp. 1 - 9
Autores principales: De Vito, Danila, Monno, Rosa, Nuccio, Federica, Legretto, Marilisa, Oliva, Marta, Coscia, Maria Franca, Dionisi, Anna Maria, Calia, Carla, Capolongo, Carmen, Pazzani, Carlo
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell 4/28/2015
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 4/28/2015
      vid: 2015
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        109274051
        109274051
        109274051
        10.1155/2015/265042
        109274051
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        atl: Diffusion and Persistence of Multidrug Resistant Salmonella Typhimurium Strains Phage Type DT120 in Southern Italy.
      aug:
        au:
          De Vito, Danila
          Monno, Rosa
          Nuccio, Federica
          Legretto, Marilisa
          Oliva, Marta
          Coscia, Maria Franca
          Dionisi, Anna Maria
          Calia, Carla
          Capolongo, Carmen
          Pazzani, Carlo
        affil: Department of Basic Medical Sciences Neurosciences and Sense Organs Medical Faculty, University of Bari Piazza G. Cesare Policlinico, 70124 Bari, Italy
      sug:
        subj:
          Drug Resistance
          Salmonella Infections Diagnosis
          Human
          Italy
          Geographic Locations
          Food Contamination Evaluation
          Genes
          Polymerase Chain Reaction
          Antiinfective Agents
      ab: Sixty-two multidrug resistant Salmonella enterica serovar Typhimurium strains isolated from 255 clinical strains collected in Southern Italy in 2006–2008 were characterised for antimicrobial resistance genes, pulsotype, and phage type. Most strains (83.9%) were resistant to ampicillin, chloramphenicol, streptomycin, sulfamethoxazole, and tetracycline (ACSSuT) encoded in 88.5% by the Salmonella genomic island (SGI1) and in 11.5% by the InH-like integron (blaOXA-30–aadA1) and catA1, sul1, and tet(B) genes. STYMXB.0061 (75%) and DT120 (84.6%) were the prevalent pulsotype and phage type identified in these strains, respectively. Five other resistance patterns were found either in single or in a low number of isolates. The pandemic clone DT104 (ACSSuT encoded by SGI1) has been identified in Italy since 1992, while strains DT120 (ACSSuT encoded by SGI1) have never been previously reported in Italy. In Europe, clinical strains DT120 have been reported from sporadic outbreaks linked to the consumption of pork products. However, none of these strains were STYMXB.0061 and SGI1 positive. The prevalent identification and persistence of DT120 isolates would suggest, in Southern Italy, a phage type shifting of the pandemic DT104 clone pulsotype STYMXB.0061. Additionally, these findings raise epidemiological concern about the potential diffusion of these emerging multidrug resistant (SGI linked) DT120 strains.
      pubtype: Academic Journal
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        research
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      ougenre: Article
    language: English
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