Structural and Function Correlation of Cone Packing Utilizing Adaptive Optics and Microperimetry.
Aim. To assess the functional aspects of cone mosaic and correlate cone packing with retinal sensitivity utilizing microperimetry in emmetropes at different eccentricities. Methods. Twenty-four healthy volunteers underwent microperimetry (MAIA Centervue, Italy) and assessment of photoreceptors using...
| Publicado en: | BioMed Research International Vol. 2015; pp. 1 - 5 |
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| Autores principales: | , , , , , , , , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
6/8/2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109274531&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 109274531 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 23146133 FT2T jtl: BioMed Research International issn: 23146133 maglogo: N pubinfo: dt: 6/8/2015 vid: 2015 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 109274531 109274531 109274531 10.1155/2015/968672 109274531 ppf: 1 ppct: 4 formats: fmt: @attributes: type: P tig: atl: Structural and Function Correlation of Cone Packing Utilizing Adaptive Optics and Microperimetry. aug: au: Supriya, Dabir Shwetha, Mangalesh Kiran Anupama, Kumar Kummelil Mathew, Kurian Berendschot, Tos T. J. M. Schouten, Jan S. A. G. Bharamshetter, Roopa Naresh, Yadav K. Rohit, Shetty Hegde, Bharath affil: Department of Retina, Narayana Nethralaya, No. 121/C, 1st R Block, Rajajinagar, Bangalore 560010, India sug: subj: Retina Analysis Diagnosis, Eye Methods Human Male Female Adult Descriptive Statistics Rods and Cones Data Analysis Software Spearman's Rank Correlation Coefficient Models, Statistical Adult: 19-44 years Male Female ab: Aim. To assess the functional aspects of cone mosaic and correlate cone packing with retinal sensitivity utilizing microperimetry in emmetropes at different eccentricities. Methods. Twenty-four healthy volunteers underwent microperimetry (MAIA Centervue, Italy) and assessment of photoreceptors using adaptive optics retinal camera, rtx1 (Imagine Eyes, Orsay, France), at 2 and 3 degrees from the foveal centre in 4 quadrants: superior, inferior, temporal, and nasal. Data was analyzed using SPSS version 17 (IBM). Spearman’s correlation tests were used to establish correlation between mean cone packing density and retinal sensitivity at different quadrants. Results. Thirteen females and 11 males (age range 20–40 years) were included. The cone density was found to be significantly different among all quadrants (temporal = 25786.68/mm2 ± 4367.07/mm2, superior = 23009.35/mm2 ± 5415.81/mm2, nasal = 22838.09/mm2 ± 4166.22/mm2, and inferior = 21097.53/mm2 ± 4235.84/mm2). A statistical significance P<0.008 was found between orthogonal meridians, that is, temporal, nasal 48624.77/mm2> superior, inferior (44106.88/mm2). A drop in retinal sensitivity was observed as the eccentricity increased P<0.05. It was also found that as cone packing density decreased retinal sensitivity also decreased P<0.05 in all quadrants. This was observed at both 2 and 3 degrees. Conclusion. It is of crucial importance to establish normative variations in cone structure-function correlation. This may help in detection of subtle pathology and its early intervention. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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