Accuracy of Colposcopically Directed Biopsy: Results from an Online Quality Assurance Programme for Colposcopy in a Population-Based Cervical Screening Setting in Italy.

Purpose. To report the accuracy of colposcopically directed biopsy in an internet-based colposcopy quality assurance programme in northern Italy. Methods. A web application was made accessible on the website of the regional Administration. Fifty-nine colposcopists out of the registered 65 logged in,...

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Publicado en:BioMed Research International Vol. 2015; pp. 1 - 7
Autores principales: Sideri, Mario, Garutti, Paola, Costa, Silvano, Cristiani, Paolo, Schincaglia, Patrizia, Sassoli de Bianchi, Priscilla, Naldoni, Carlo, Bucchi, Lauro
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell 6/9/2015
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 6/9/2015
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2015/614035
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        atl: Accuracy of Colposcopically Directed Biopsy: Results from an Online Quality Assurance Programme for Colposcopy in a Population-Based Cervical Screening Setting in Italy.
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        au:
          Sideri, Mario
          Garutti, Paola
          Costa, Silvano
          Cristiani, Paolo
          Schincaglia, Patrizia
          Sassoli de Bianchi, Priscilla
          Naldoni, Carlo
          Bucchi, Lauro
        affil: Preventive Gynaecology Unit, European Institute of Oncology, Via Giuseppe Ripamonti 435, 20141 Milan, Italy
      sug:
        subj:
          Cervix Neoplasms Diagnosis
          Colposcopy
          Biopsy
          Human
          Italy
          Academic Medical Centers
          Quality Assurance
          Sensitivity and Specificity
          Multivariate Analysis
          Severity of Illness
          Neoplasm Staging
          Female
          Adult
          Middle Age
          Confidence Intervals
          Chi Square Test
          Odds Ratio
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Female
      ab: Purpose. To report the accuracy of colposcopically directed biopsy in an internet-based colposcopy quality assurance programme in northern Italy. Methods. A web application was made accessible on the website of the regional Administration. Fifty-nine colposcopists out of the registered 65 logged in, viewed a posted set of 50 digital colpophotographs, classified them for colposcopic impression and need for biopsy, and indicated the most appropriate site for biopsy with a left-button mouse click on the image. Results. Total biopsy failure rate, comprising both nonbiopsy and incorrect selection of biopsy site, was 0.20 in CIN1, 0.11 in CIN2, 0.09 in CIN3, and 0.02 in carcinoma. Errors in the selection of biopsy site were stable between 0.08 and 0.09 in the three grades of CIN while decreasing to 0.01 in carcinoma. In multivariate analysis, the risk of incorrect selection of biopsy site was 1.97 for CIN2, 2.52 for CIN3, and 0.29 for carcinoma versus CIN1. Conclusions. Although total biopsy failure rate decreased regularly with increasing severity of histological diagnosis, the rate of incorrect selection of biopsy site was stable up to CIN3. In multivariate analysis, CIN2 and CIN3 had an independently increased risk of incorrect selection of biopsy site.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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