Optimization of Culture Conditions for Production of the Anti-Leukemic Glutaminase Free L-Asparaginase by Newly Isolated Streptomyces olivaceus NEAE-119 Using Response Surface Methodology.

Among the antitumor drugs, bacterial enzyme L-asparaginase has been employed as the most effective chemotherapeutic agent in pediatric oncotherapy especially for acute lymphoblastic leukemia. Glutaminase free L-asparaginase producing actinomycetes were isolated from soil samples collected from Egypt...

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Publicado en:BioMed Research International Vol. 2015; pp. 1 - 18
Autores principales: El-Naggar, Noura El-Ahmady, Moawad, Hassan, El-Shweihy, Nancy M., El-Ewasy, Sara M.
Formato: equations & formulas pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell 6/9/2015
Acceso en línea:Ver este registro en EBSCOhost