Validation and Development of a New Automatic Algorithm for Time-Resolved Segmentation of the Left Ventricle in Magnetic Resonance Imaging.

Introduction. Manual delineation of the left ventricle is clinical standard for quantification of cardiovascular magnetic resonance images despite being time consuming and observer dependent. Previous automatic methods generally do not account for one major contributor to stroke volume, the long-axi...

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Publicado en:BioMed Research International Vol. 2015; pp. 1 - 13
Autores principales: Tufvesson, Jane, Hedström, Erik, Steding-Ehrenborg, Katarina, Carlsson, Marcus, Arheden, Håkan, Heiberg, Einar
Formato: diagnostic images research tables/charts Journal Article
Publicado: Wiley-Blackwell 6/21/2015
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 6/21/2015
      vid: 2015
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2015/970357
        109274647
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        atl: Validation and Development of a New Automatic Algorithm for Time-Resolved Segmentation of the Left Ventricle in Magnetic Resonance Imaging.
      aug:
        au:
          Tufvesson, Jane
          Hedström, Erik
          Steding-Ehrenborg, Katarina
          Carlsson, Marcus
          Arheden, Håkan
          Heiberg, Einar
        affil: Department of Clinical Physiology, Lund University Hospital, Lund University, 221 85 Lund, Sweden
      sug:
        subj:
          Cardiovascular System Physiology
          Heart Ventricle, Left Physiology
          Magnetic Resonance Imaging
          Algorithms Evaluation
          Human
          Descriptive Statistics
          Validation Studies
          Stroke Volume
          Paired T-Tests
          Linear Regression
          Ventricular Ejection Fraction
          Diastolic Pressure
          Interrater Reliability
          Funding Source
      ab: Introduction. Manual delineation of the left ventricle is clinical standard for quantification of cardiovascular magnetic resonance images despite being time consuming and observer dependent. Previous automatic methods generally do not account for one major contributor to stroke volume, the long-axis motion. Therefore, the aim of this study was to develop and validate an automatic algorithm for time-resolved segmentation covering the whole left ventricle, including basal slices affected by long-axis motion. Methods. Ninety subjects imaged with a cine balanced steady state free precession sequence were included in the study (training set n=40, test set n=50). Manual delineation was reference standard and second observer analysis was performed in a subset (n=25). The automatic algorithm uses deformable model with expectation-maximization, followed by automatic removal of papillary muscles and detection of the outflow tract. Results. The mean differences between automatic segmentation and manual delineation were EDV −11 mL, ESV 1 mL, EF −3%, and LVM 4 g in the test set. Conclusions. The automatic LV segmentation algorithm reached accuracy comparable to interobserver for manual delineation, thereby bringing automatic segmentation one step closer to clinical routine. The algorithm and all images with manual delineations are available for benchmarking.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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