Compressed Sensing for fMRI: Feasibility Study on the Acceleration of Non-EPI fMRI at 9.4T.

Conventional functional magnetic resonance imaging (fMRI) technique known as gradient-recalled echo (GRE) echo-planar imaging (EPI) is sensitive to image distortion and degradation caused by local magnetic field inhomogeneity at high magnetic fields. Non-EPI sequences such as spoiled gradient echo a...

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Publicado en:BioMed Research International Vol. 2015; pp. 1 - 25
Autores principales: Han, Paul Kyu, Park, Sung-Hong, Kim, Seong-Gi, Ye, Jong Chul
Formato: Journal Article
Publicado: Wiley-Blackwell 8/27/2015
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 8/27/2015
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      pub: Wiley-Blackwell
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        atl: Compressed Sensing for fMRI: Feasibility Study on the Acceleration of Non-EPI fMRI at 9.4T.
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        au:
          Han, Paul Kyu
          Park, Sung-Hong
          Kim, Seong-Gi
          Ye, Jong Chul
        affil: Bio Imaging and Signal Processing Lab, Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology (KAIST), 373-1 Guseong-dong, Yuseong-gu, Daejeon 305-701, Republic of Korea
      sug:
      ab: Conventional functional magnetic resonance imaging (fMRI) technique known as gradient-recalled echo (GRE) echo-planar imaging (EPI) is sensitive to image distortion and degradation caused by local magnetic field inhomogeneity at high magnetic fields. Non-EPI sequences such as spoiled gradient echo and balanced steady-state free precession (bSSFP) have been proposed as an alternative high-resolution fMRI technique; however, the temporal resolution of these sequences is lower than the typically used GRE-EPI fMRI. One potential approach to improve the temporal resolution is to use compressed sensing (CS). In this study, we tested the feasibility of k-t FOCUSS-one of the high performance CS algorithms for dynamic MRI-for non-EPI fMRI at 9.4T using the model of rat somatosensory stimulation. To optimize the performance of CS reconstruction, different sampling patterns and k-t FOCUSS variations were investigated. Experimental results show that an optimized k-t FOCUSS algorithm with acceleration by a factor of 4 works well for non-EPI fMRI at high field under various statistical criteria, which confirms that a combination of CS and a non-EPI sequence may be a good solution for high-resolution fMRI at high fields.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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