Oral and inhaled p38 MAPK inhibitors: effects on inhaled LPS challenge in healthy subjects.

Background: Inhaled LPS causes neutrophilic airway inflammation in healthy subjects. We compared the effects of p38 MAPK inhibitors and fluticasone propionate on the LPS response. Methods: Three randomised, double-blind, placebo-controlled, single dose crossover studies were performed. Active treatm...

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Publicado en:	European Journal of Clinical Pharmacology Vol. 71; no. 10; pp. 1175 - 1185
Autores principales:	Singh, Dave, Siew, Leonard, Christensen, Jared, Plumb, Jonathan, Clarke, Graham, Greenaway, Steve, Perros-Huguet, Christelle, Clarke, Nick, Kilty, Iain, Tan, Lisa
Formato:	research tables/charts randomized controlled trial Journal Article
Publicado:	Springer Nature Oct2015
Acceso en línea:	Ver este registro en EBSCOhost