Postoperative pyoderma gangrenosum (PG): the Mayo Clinic experience of 20 years from 1994 through 2014.

Background: Postoperative pyoderma gangrenosum (PG) is a neutrophilic dermatosis characterized by the development of PG-type lesions within surgical sites.Objective: We sought to characterize postoperative PG as a distinct subtype of PG for earlier recognition and prevention of improper therapy.Meth...

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Publicado en:Journal of the American Academy of Dermatology Vol. 73; no. 4; pp. 615 - 623
Autores principales: Tolkachjov, Stanislav N., Fahy, Aodhnait S., Wetter, David A., Brough, Kevin R., Bridges, Alina G., Davis, Mark D.P., el-Azhary, Rokea A., McEvoy, Marian T., Camilleri, Michael J.
Formato: research Journal Article
Publicado: Elsevier B.V. Oct2015
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2015
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      pub: Elsevier B.V.
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        atl: Postoperative pyoderma gangrenosum (PG): the Mayo Clinic experience of 20 years from 1994 through 2014.
      aug:
        au:
          Tolkachjov, Stanislav N.
          Fahy, Aodhnait S.
          Wetter, David A.
          Brough, Kevin R.
          Bridges, Alina G.
          Davis, Mark D.P.
          el-Azhary, Rokea A.
          McEvoy, Marian T.
          Camilleri, Michael J.
        affil: Department of Dermatology, Mayo Clinic, Rochester, Minnesota
      sug:
        subj:
          Pyoderma Gangrenosum Epidemiology
          Pyoderma Gangrenosum Therapy
          Surgery, Operative Adverse Effects
          Postoperative Complications Therapy
          Postoperative Complications Epidemiology
          Demography
          Prospective Studies
          Risk Assessment
          Early Diagnosis
          Academic Medical Centers
          Female
          Treatment Outcomes
          Surgery, Operative Classification
          Male
          Prevalence
          Aged
          Adult
          Pyoderma Gangrenosum Etiology
          Retrospective Design
          Severity of Illness Indices
          Middle Age
          Postoperative Complications Diagnosis
          Resource Databases
          Human
          Aged: 65+ years
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Female
          Male
      ab: Background: Postoperative pyoderma gangrenosum (PG) is a neutrophilic dermatosis characterized by the development of PG-type lesions within surgical sites.Objective: We sought to characterize postoperative PG as a distinct subtype of PG for earlier recognition and prevention of improper therapy.Methods: We conducted a retrospective chart review of patients with nonperistomal postoperative PG at Mayo Clinic from 1994 to 2014.xResults: Eighteen patients had postoperative PG with an average age of 58 years. Fifteen (83%) were female. Among patients with postoperative PG, 4 (22%) had an associated systemic disease traditionally associated with PG. Sites of postoperative PG included 7 breast (38%), 7 abdomen (38%), 1 back, 1 shoulder, 1 ankle, and 1 scrotum, witxxh breast reconstruction being the most common surgery. The average time to symptoms was 11 days. No patients had a fever. Eight (44%) had documented anemia and 5 (27%) had leukocytosis. Antibiotics and systemic corticosteroids were initiated in 10 (56%) and 14 (83%), respectively. Debridement was done in 11 (61%) patients.Limitations: Small sample size and retrospective study are limitations.Conclusion: Postoperative PG is a rare surgical complication with predilection for the breast and abdomen of females and has less association with systemic disease than idiopathic PG. Early recognition may prevent unnecessary debridements and morbidity.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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