An Artificial Immune System-Based Support Vector Machine Approach for Classifying Ultrasound Breast Tumor Images.

A rapid and highly accurate diagnostic tool for distinguishing benign tumors from malignant ones is required owing to the high incidence of breast cancer. Although various computer-aided diagnosis (CAD) systems have been developed to interpret ultrasound images of breast tumors, feature selection an...

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Bibliographic Details
Published in:Journal of Digital Imaging Vol. 28; no. 5; pp. 576 - 586
Main Authors: Wu, Wen-Jie, Lin, Shih-Wei, Moon, Woo
Format: diagnostic images equations & formulas research tables/charts Journal Article
Published: Springer Nature Oct2015
Online Access:View this record in EBSCOhost
Description
Summary:A rapid and highly accurate diagnostic tool for distinguishing benign tumors from malignant ones is required owing to the high incidence of breast cancer. Although various computer-aided diagnosis (CAD) systems have been developed to interpret ultrasound images of breast tumors, feature selection and the setting of parameters are still essential to classification accuracy and the minimization of computational complexity. This work develops a highly accurate CAD system that is based on a support vector machine (SVM) and the artificial immune system (AIS) algorithm for evaluating breast tumors. Experiments demonstrate that the accuracy of the proposed CAD system for classifying breast tumors is 96.67 %. The sensitivity, specificity, PPV, and NPV of the proposed CAD system are 96.67, 96.67, 95.60, and 97.48 %, respectively. The receiver operator characteristic (ROC) area index A is 0.9827. Hence, the proposed CAD system can reduce the number of biopsies and yield useful results that assist physicians in diagnosing breast tumors.