Performance investigation of SP3 and diffusion approximation for three-dimensional whole-body optical imaging of small animals.
The third-order simplified harmonic spherical approximation (SP3) and diffusion approximation (DA) equations have been widely used in the three-dimensional (3D) whole-body optical imaging of small animals. With different types of tissues, which were classified by the ratio of µ s'/µ ɑ, the two equat...
| Publicado en: | Medical & Biological Engineering & Computing Vol. 53; no. 9; pp. 805 - 815 |
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| Autores principales: | , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Sep2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109466529&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 109466529 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01400118 PO0 jtl: Medical & Biological Engineering & Computing issn: 01400118 maglogo: N pubinfo: dt: Sep2015 vid: 53 iid: 9 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 109466529 109466529 NLM25850985 109466529 10.1007/s11517-015-1293-8 NLM25850985 109466529 ppf: 805 ppct: 10 formats: fmt: @attributes: type: P tig: atl: Performance investigation of SP3 and diffusion approximation for three-dimensional whole-body optical imaging of small animals. aug: au: Yang, Defu Chen, Xueli Cao, Xu Wang, Jing Liang, Jimin Tian, Jie affil: Engineering Research Center of Molecular and Neuro Imaging of Ministry of Education, School of Life Science and Technology, Xidian University, Xi'an 710071 China sug: subj: Algorithms Imaging, Three-Dimensional Methods Diagnostic Imaging Methods Computer Simulation Systems Analysis Mice Absorption Diffusion Animals Light Finite Element Analysis Animal Studies ab: The third-order simplified harmonic spherical approximation (SP3) and diffusion approximation (DA) equations have been widely used in the three-dimensional (3D) whole-body optical imaging of small animals. With different types of tissues, which were classified by the ratio of µ s'/µ ɑ, the two equations have their own application scopes. However, the classification criterion was blurring and unreasonable, and the scope has not been systematically investigated until now. In this study, a new criterion for classifying tissues was established based on the absolute value of absorption and reduced scattering coefficients. Using the newly defined classification criterion, the performance and applicability of the SP3 and DA equations were evaluated with a series of investigation experiments. Extensive investigation results showed that the SP3 equation exhibited a better performance and wider applicability than the DA one in most of the observed cases, especially in tissues of low-scattering-low-absorption and low-scattering-high-absorption range. For the case of tissues with the high-scattering-low-absorption properties, a similar performance was observed for both the SP3 and the DA equations, in which case the DA was the preferred option for 3D whole-body optical imaging. Results of this study would provide significant reference for the study of hybrid light transport models. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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