Advanced neuroimaging applied to veterans and service personnel with traumatic brain injury: state of the art and potential benefits.

Traumatic brain injury (TBI) remains one of the most prevalent forms of morbidity among Veterans and Service Members, particularly for those engaged in the conflicts in Iraq and Afghanistan. Neuroimaging has been considered a potentially useful diagnostic and prognostic tool across the spectrum of T...

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Publicado en:Brain Imaging & Behavior Vol. 9; no. 3; pp. 367 - 403
Autores principales: Wilde, Elisabeth, Bouix, Sylvain, Tate, David, Lin, Alexander, Newsome, Mary, Taylor, Brian, Stone, James, Montier, James, Gandy, Samuel, Biekman, Brian, Shenton, Martha, York, Gerald, Wilde, Elisabeth A, Tate, David F, Lin, Alexander P, Newsome, Mary R, Taylor, Brian A, Stone, James R, Gandy, Samuel E, Shenton, Martha E
Formato: review Journal Article
Publicado: Springer Nature Sep2015
Acceso en línea:Ver este registro en EBSCOhost
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          Wilde, Elisabeth
          Bouix, Sylvain
          Tate, David
          Lin, Alexander
          Newsome, Mary
          Taylor, Brian
          Stone, James
          Montier, James
          Gandy, Samuel
          Biekman, Brian
          Shenton, Martha
          York, Gerald
          Wilde, Elisabeth A
          Tate, David F
          Lin, Alexander P
          Newsome, Mary R
          Taylor, Brian A
          Stone, James R
          Gandy, Samuel E
          Shenton, Martha E
        affil: Department of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston USA
      sug:
        subj:
          Brain Injuries Pathology
          Neuroradiography Methods
          Veterans
          Brain Physiopathology
          Brain Injuries Therapy
          Military Personnel
          Brain Injuries Diagnosis
          Brain Pathology
          Brain Injuries Physiopathology
          Funding Source
      ab: Traumatic brain injury (TBI) remains one of the most prevalent forms of morbidity among Veterans and Service Members, particularly for those engaged in the conflicts in Iraq and Afghanistan. Neuroimaging has been considered a potentially useful diagnostic and prognostic tool across the spectrum of TBI generally, but may have particular importance in military populations where the diagnosis of mild TBI is particularly challenging, given the frequent lack of documentation on the nature of the injuries and mixed etiologies, and highly comorbid with other disorders such as post-traumatic stress disorder, depression, and substance misuse. Imaging has also been employed in attempts to understand better the potential late effects of trauma and to evaluate the effects of promising therapeutic interventions. This review surveys the use of structural and functional neuroimaging techniques utilized in military studies published to date, including the utilization of quantitative fluid attenuated inversion recovery (FLAIR), susceptibility weighted imaging (SWI), volumetric analysis, diffusion tensor imaging (DTI), magnetization transfer imaging (MTI), positron emission tomography (PET), magnetoencephalography (MEG), task-based and resting state functional MRI (fMRI), arterial spin labeling (ASL), and magnetic resonance spectroscopy (MRS). The importance of quality assurance testing in current and future research is also highlighted. Current challenges and limitations of each technique are outlined, and future directions are discussed.
      pubtype: Academic Journal
      doctype:
        review
        Journal Article
      ougenre: Article
    language: English
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