In vivo analysis of physiological 3D blood flow of cerebral veins.
Objectives: To visualize and quantify physiological blood flow of intracranial veins in vivo using time-resolved, 3D phase-contrast MRI (4D flow MRI), and to test measurement accuracy.Methods: Fifteen healthy volunteers underwent repeated ECG-triggered 4D flow MRI (3 Tesla, 32-channel head coil). In...
| Publicado en: | European Radiology Vol. 25; no. 8; pp. 2371 - 2381 |
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| Autores principales: | , , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Aug2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109594929&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 109594929 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Aug2015 vid: 25 iid: 8 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 109594929 103687126 NLM25638218 2013091296 10.1007/s00330-014-3587-x NLM25638218 109594929 ppf: 2371 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: In vivo analysis of physiological 3D blood flow of cerebral veins. aug: au: Schuchardt, Florian Schroeder, Laure Anastasopoulos, Constantin Markl, Michael Bäuerle, Jochen Hennemuth, Anja Drexl, Johann Valdueza, José M Mader, Irina Harloff, Andreas sug: subj: Cerebral Veins Physiology Cranial Sinuses Physiology Adult Imaging, Three-Dimensional Young Adult Sinus Thrombosis, Intracranial Physiopathology Magnetic Resonance Angiography Ultrasonography, Doppler, Duplex Male Female Prospective Studies Blood Flow Velocity Physiology Cerebrovascular Circulation Physiology Diagnostic Imaging Reproducibility of Results Adult: 19-44 years Male Female ab: Objectives: To visualize and quantify physiological blood flow of intracranial veins in vivo using time-resolved, 3D phase-contrast MRI (4D flow MRI), and to test measurement accuracy.Methods: Fifteen healthy volunteers underwent repeated ECG-triggered 4D flow MRI (3 Tesla, 32-channel head coil). Intracranial venous blood flow was analysed using dedicated software allowing for blood flow visualization and quantification in analysis planes at the superior sagittal, straight, and transverse sinuses. MRI was evaluated for intra- and inter-observer agreement and scan-rescan reproducibility. Measurements of the transverse sinuses were compared with transcranial two-dimensional duplex ultrasound.Results: Visualization of 3D blood flow within cerebral sinuses was feasible in 100 % and within at least one deep cerebral vein in 87 % of the volunteers. Blood flow velocity/volume increased along the superior sagittal sinus and was lower in the left compared to the right transverse sinus. Intra- and inter-observer reliability and reproducibility of blood flow velocity (mean difference 0.01/0.02/0.02 m/s) and volume (mean difference 0.0002/-0.0003/0.00003 l/s) were good to excellent. High/low velocities were more pronounced (8 % overestimation/9 % underestimation) in MRI compared to ultrasound.Conclusions: Four-dimensional flow MRI reliably visualizes and quantifies three-dimensional cerebral venous blood flow in vivo and is promising for studies in patients with sinus thrombosis and related diseases.Key Points: • 4D flow MRI can be used to visualize and quantify physiological cerebral venous haemodynamics • Flow quantification within cerebral sinuses reveals high reliability and accuracy of 4D flow MRI • Blood flow volume and velocity increase along the superior sagittal sinus • Limited spatial resolution currently precludes flow quantification in small cerebral veins. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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