Structural and Function Correlation of Cone Packing Utilizing Adaptive Optics and Microperimetry.
Aim: To assess the functional aspects of cone mosaic and correlate cone packing with retinal sensitivity utilizing microperimetry in emmetropes at different eccentricities.Methods: Twenty-four healthy volunteers underwent microperimetry (MAIA Centervue, Italy) and assessment of photoreceptors using...
| Publicado en: | BioMed Research International Vol. 2015; pp. 968672 - 968673 |
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| Autores principales: | , , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Wiley-Blackwell
1/1/2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109596632&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 109596632 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 23146133 FT2T jtl: BioMed Research International issn: 23146133 maglogo: N pubinfo: dt: 1/1/2015 vid: 2015 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 109596632 NLM26167509 2013093353 10.1155/2015/968672 NLM26167509 PMC4475732 109596632 ppf: 968672 ppct: 1 formats: fmt: @attributes: type: P tig: atl: Structural and Function Correlation of Cone Packing Utilizing Adaptive Optics and Microperimetry. aug: au: Supriya, Dabir Shwetha, Mangalesh Kiran Anupama, Kumar Kummelil Mathew, Kurian Berendschot, Tos T J M Schouten, Jan S A G Bharamshetter, Roopa Naresh, Yadav K Rohit, Shetty Hegde, Bharath sug: ab: Aim: To assess the functional aspects of cone mosaic and correlate cone packing with retinal sensitivity utilizing microperimetry in emmetropes at different eccentricities.Methods: Twenty-four healthy volunteers underwent microperimetry (MAIA Centervue, Italy) and assessment of photoreceptors using adaptive optics retinal camera, rtx1 (Imagine Eyes, Orsay, France), at 2 and 3 degrees from the foveal centre in 4 quadrants: superior, inferior, temporal, and nasal. Data was analyzed using SPSS version 17 (IBM). Spearman's correlation tests were used to establish correlation between mean cone packing density and retinal sensitivity at different quadrants.Results: Thirteen females and 11 males (age range 20-40 years) were included. The cone density was found to be significantly different among all quadrants (temporal = 25786.68/mm(2) ± 4367.07/mm(2), superior = 23009.35/mm(2) ± 5415.81/mm(2), nasal = 22838.09/mm(2) ± 4166.22/mm(2), and inferior = 21097.53/mm(2) ± 4235.84/mm(2)). A statistical significance (P < 0.008) was found between orthogonal meridians, that is, temporal, nasal (48624.77/mm(2))> superior, inferior (44106.88/mm(2)). A drop in retinal sensitivity was observed as the eccentricity increased (P < 0.05). It was also found that as cone packing density decreased retinal sensitivity also decreased (P < 0.05) in all quadrants. This was observed at both 2 and 3 degrees.Conclusion: It is of crucial importance to establish normative variations in cone structure-function correlation. This may help in detection of subtle pathology and its early intervention. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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