Comparison of myocardial F-18 FDG uptake between overnight and non-overnight fasting in non-diabetic healthy subjects.

Purpose: To evaluate whether an overnight or non-overnight fast for suppressing physiological FDG uptake by the myocardium is better in non-diabetic healthy subjects before F-18 FDG PET/CT studies.Materials and Methods: One hundred two subjects who underwent whole-body F-18 FDG PET/CT for routine he...

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Publicado en:Japanese Journal of Radiology Vol. 33; no. 7; pp. 385 - 392
Autores principales: Lee, Hyo Young, Nam, Hyun-Yeol, Shin, Seong Kyu
Formato: research Journal Article
Publicado: Springer Nature Jul2015
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul2015
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      pub: Springer Nature
      place: New York, New York
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        atl: Comparison of myocardial F-18 FDG uptake between overnight and non-overnight fasting in non-diabetic healthy subjects.
      aug:
        au:
          Lee, Hyo Young
          Nam, Hyun-Yeol
          Shin, Seong Kyu
      sug:
        subj:
          Fasting
          Fludeoxyglucose F 18 Metabolism
          Myocardium Metabolism
          Male
          Retrospective Design
          Female
          Time Factors
          Estradiol Analogs and Derivatives
          Human
          Middle Age
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Middle Aged: 45-64 years
          Male
          Female
      ab: Purpose: To evaluate whether an overnight or non-overnight fast for suppressing physiological FDG uptake by the myocardium is better in non-diabetic healthy subjects before F-18 FDG PET/CT studies.Materials and Methods: One hundred two subjects who underwent whole-body F-18 FDG PET/CT for routine health checkups were retrospectively reviewed. For quantitative assessment, a region of interest was drawn around the entire left ventricle visible in the axial view containing the highest visual uptake in order to measure the maximum standardized uptake value (SUV max). FDG uptake in the myocardium was visually graded as follows: grade 0 = minimal, 1 = mostly minimal or mild, 2 = mostly intense or moderate, and 3 = homogeneously intense. Adequate suppression of myocardial uptake was quantitatively defined as a SUV max ≤ 5.0 and grade 0 by visual assessment.Results: With regard to the SUV max, myocardial uptake was not different between the overnight and the non-overnight fasting subjects (P = 0.753). In subjects who had adequate suppression of myocardial uptake, no significant difference was observed between the overnight and non-overnight fasting subjects either in terms of visual or quantitative assessment (P = 0.539 and P = 0.678, respectively).Conclusion: Both overnight and non-overnight fasts are not adequate for suppressing the physiological uptake of FDG by the myocardium.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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